Amlodipine and Rayaldee drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amlodipine (amlodipine besylate) and Rayaldee (calcifediol). Common drug interactions include death among females and hip arthroplasty among males.

The phase IV clinical study analyzes what interactions people have when they take Amlodipine and Rayaldee. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

What is Rayaldee?

Rayaldee has active ingredients of calcifediol. eHealthMe is studying from 342 Rayaldee users. Check the latest studies of Rayaldee.

On Jul, 31, 2026

37 people who take Amlodipine and Rayaldee together, and have interactions are studied.

Amlodipine and Rayaldee drug interactions.

What are the common drug interactions of Amlodipine and Rayaldee, by gender? *:

female:

Death
Dyspnoea (difficult or laboured respiration)
Abdominal discomfort
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Dry eye (lack of adequate tears)
Gout (uric acid crystals building up in the body)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)

male:

Hip arthroplasty
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Death
Fatigue (feeling of tiredness)
Osteopenia (a condition where bone mineral density is lower than normal)
Cytomegalovirus infection
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Rash
Anxiety

What are the common drug interactions of Amlodipine and Rayaldee, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cytomegalovirus infection

40-49:

Hip arthroplasty
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Bone density decreased
Renal failure (kidney dysfunction)
Bone loss
Osteopenia (a condition where bone mineral density is lower than normal)

50-59:

Death
Injection site pain
Injection site pruritus (severe itching at injection site)
Injection site swelling

60+:

Death
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Vomiting
Cardiac arrest
Contusion (a type of hematoma of tissue in which capillaries)
Diabetes mellitus inadequate control
Diarrhoea
Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 6 people, 16.22%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 5 people, 13.51%
Hiv Infection: 4 people, 10.81%
Rickets (softening of bones): 3 people, 8.11%
Multiple Myeloma (cancer of the plasma cells): 3 people, 8.11%
Cushing's Syndrome (obesity, a rounded face, increased fat): 3 people, 8.11%
Secondary Hyperthyroidism: 2 people, 5.41%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 5.41%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 5.41%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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