Amoxicillin and Aldara drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Aldara (imiquimod). Common drug interactions include deep vein thrombosis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Aldara. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Aldara?

Aldara has active ingredients of imiquimod. It is often used in genital warts. eHealthMe is studying from 2,554 Aldara users. Check the latest studies of Aldara.



On Jul, 26, 2026

40 people who take Amoxicillin and Aldara together, and have interactions are studied.

Amoxicillin and Aldara drug interactions.

What are the common drug interactions of Amoxicillin and Aldara, by gender? *:

female:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Depressed mood
  3. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  4. Ear infection
  5. Emotional distress
  6. Encephalitis (inflammation of the brain)
  7. Erythema (redness of the skin)
  8. Fear
  9. Femur fracture
  10. Fracture displacement

male:

  1. Pain
  2. Anxiety
  3. Groin pain
  4. Hepatic cyst
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Influenza like illness
  7. Intervertebral disc disorder (spinal disc disorder)
  8. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  9. Lung neoplasm malignant (cancer tumour of lung)
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Amoxicillin and Aldara, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Depressed level of consciousness
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Petit mal epilepsy (absence seizure)
  4. Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
  5. Staring (a prolonged gaze or fixed look)
  6. Headache (pain in head)
  7. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  8. Drug hypersensitivity
  9. Joint stiffness
  10. Joint swelling

10-19:

  1. Anxiety
  2. Aphasia (damage to the parts of the brain that control language)
  3. Balance disorder
  4. Cerebral infarction (less blood supply to brain resulting tissue damage)
  5. Dizziness
  6. Emotional distress
  7. Gait disturbance
  8. Hyperaesthesia
  9. Mobility decreased (ability to move is reduced)
  10. Pain

20-29:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Abdominal pain upper
  3. Fear
  4. Portal vein thrombosis (venous thrombosis affecting the hepatic portal vein)
  5. Pulmonary embolism (blockage of the main artery of the lung)

30-39:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Bone density decreased
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Laryngeal ulceration (ulcer on larynx)
  8. Muscle spasms (muscle contraction)
  9. Oesophageal reflux (moving the food downwards)
  10. Osteonecrosis (death of bone)

40-49:

  1. Pelvic fracture
  2. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  3. Pneumonia
  4. Pulmonary mass
  5. Spinal osteoarthritis (joint cartilage loss in spine)
  6. Tooth extraction
  7. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  8. Leukoplakia oral (white and gray patches inside the mouth)
  9. Osteonecrosis (death of bone)
  10. Dental caries

50-59:

  1. Application site irritation
  2. Burning sensation
  3. Vaginal discharge
  4. Vaginal haemorrhage (vaginal bleeding)

60+:

  1. Fall
  2. Renal failure (kidney dysfunction)
  3. Decreased immune responsiveness
  4. Depressed mood
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Ear infection
  7. Emotional distress
  8. Encephalitis (inflammation of the brain)
  9. Erythema (redness of the skin)
  10. Femur fracture

What are the existing conditions these people have? *

  1. Pain: 11 people, 27.50%
  2. Birth Control: 6 people, 15.00%
  3. Osteolysis (dissolution of bone): 6 people, 15.00%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.50%
  5. Depression: 4 people, 10.00%
  6. Stress And Anxiety: 3 people, 7.50%
  7. Hiv Infection: 3 people, 7.50%
  8. Cough: 3 people, 7.50%
  9. High Blood Pressure: 3 people, 7.50%
  10. Otitis (ear infection): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and Aldara?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amoxicillin and Aldara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aldara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aldara and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin and imiquimod (the active ingredients of Amoxicillin and Aldara, respectively), and Amoxicillin and Aldara (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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