Amoxicillin and Apidra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Apidra (insulin glulisine recombinant). Common drug interactions include episcleritis among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Apidra. It is created by eHealthMe based on reports of 94 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Apidra?

Apidra has active ingredients of insulin glulisine recombinant. It is often used in diabetes. eHealthMe is studying from 10,548 Apidra users. Check the latest studies of Apidra.

On Jul, 18, 2026

94 people who take Amoxicillin and Apidra together, and have interactions are studied.

Amoxicillin and Apidra drug interactions.

What are the common drug interactions of Amoxicillin and Apidra, by gender? *:

female:

Episcleritis (acute inflammatory disorder of the episclera of eye)
Eye pain
Gamma-glutamyltransferase increased
Lymphocyte count decreased
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Sensory disturbance (sense disturbance)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin burning sensation
Vision blurred
Burning sensation

male:

Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Spinal pain (pain in spine)
Klebsiella infection
Pericarditis (inflammation of the pericardium)
Therapeutic response decreased (less preventive response)
Bronchial haemorrhage (bleeding in bronchia)
Cough
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Plasma cell myeloma (cancer that begins in plasma cells)

What are the common drug interactions of Amoxicillin and Apidra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Chronic kidney disease
Ketoacidosis (high concentrations of ketone bodies in blood)

10-19:

n/a

20-29:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Cerebral haemorrhage (bleeding within the brain)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Biliary colic
Cardiovascular disorder (heart diseases)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diabetic coma

40-49:

Chronic kidney disease
Dizziness
Alanine aminotransferase increased
Cataract subcapsular (cataracts that affect the back of the lens)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Diabetes mellitus inadequate control
Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Episcleritis (acute inflammatory disorder of the episclera of eye)
Eye pain

50-59:

Hot flush (sudden feelings of heat)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypertriglyceridaemia (excess of triglycerides in the blood)
Injury
Insomnia (sleeplessness)
Joint range of motion decreased (disease of joint movement)
Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation)
Lipids increased (excess lipid in body)
Loss of consciousness
Memory impairment

60+:

Neutropenia (an abnormally low number of neutrophils)
Renal failure (kidney dysfunction)
Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Pyrexia (fever)
Rash

What are the existing conditions these people have? *

Pain: 50 people, 53.19%
High Blood Pressure: 22 people, 23.40%
Multiple Myeloma (cancer of the plasma cells): 20 people, 21.28%
Stress And Anxiety: 19 people, 20.21%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 17.02%
Pericarditis (inflammation of the pericardium): 16 people, 17.02%
Depression: 15 people, 15.96%
Constipation: 13 people, 13.83%
Type 2 Diabetes: 12 people, 12.77%
Insomnia (sleeplessness): 11 people, 11.70%

* Approximation only. Some reports may have incomplete information.

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