Amoxicillin and Benlysta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Benlysta (belimumab). Common drug interactions include urinary tract infection among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Benlysta. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,236 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Benlysta?

Benlysta has active ingredients of belimumab. It is often used in systemic lupus erythematosus. eHealthMe is studying from 23,528 Benlysta users. Check the latest studies of Benlysta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

80 people who take Amoxicillin and Benlysta together, and have interactions are studied.

Amoxicillin and Benlysta drug interactions.

What are the common drug interactions of Amoxicillin and Benlysta, by gender? *:

female:

  1. Urinary tract infection
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Weight decreased
  4. Rash
  5. Asthenia (weakness)
  6. Pain
  7. Cystitis (inflammation of the wall of the bladder)
  8. Jaw disorder (jaw disease)
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Swelling

male:

  1. Interstitial lung disease
  2. Acute myocardial infarction (acute heart attack)
  3. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  4. Hypertensive heart disease
  5. Pneumonia
  6. Cell marker increased

What are the common drug interactions of Amoxicillin and Benlysta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Myalgia (muscle pain)

20-29:

  1. Burning sensation
  2. Insomnia (sleeplessness)
  3. Pain in extremity
  4. Peripheral swelling

30-39:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Headache (pain in head)
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  5. Rash
  6. Weight decreased
  7. Acute febrile neutrophilic dermatosis (skin disease characterized by the sudden onset of fever, leukocytosis, and tender)
  8. Anaemia (lack of blood)
  9. Asthma
  10. Asthmatic crisis

40-49:

  1. Headache (pain in head)
  2. Drug hypersensitivity
  3. Hypersensitivity
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Tooth extraction
  6. Blood pressure increased
  7. Dyspnoea (difficult or laboured respiration)
  8. Erythema (redness of the skin)
  9. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Neuropathy peripheral (surface nerve damage)
  2. Oral pain
  3. Osteitis (a general term for inflammation of bone)
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Osteomyelitis chronic (long lasting infection of bone marrow)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Osteoporosis (bones weak and more likely to break)
  9. Pain
  10. Pain in extremity

60+:

  1. Anxiety
  2. Cardiac disorder
  3. Headache (pain in head)
  4. Insomnia (sleeplessness)
  5. Jaw disorder (jaw disease)
  6. Nausea (feeling of having an urge to vomit)
  7. Pain
  8. Renal disorder (kidney disease)
  9. Chest pain
  10. Confusional state

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 10.00%
  2. Diabetes: 7 people, 8.75%
  3. Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 5 people, 6.25%
  4. Depression: 5 people, 6.25%
  5. Acne (skin problems that cause pimples): 5 people, 6.25%
  6. Pharyngeal Inflammation: 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and Benlysta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amoxicillin and Benlysta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Benlysta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Benlysta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin and belimumab (the active ingredients of Amoxicillin and Benlysta, respectively), and Amoxicillin and Benlysta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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