Amoxicillin and Dayquil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Dayquil (acetaminophen; dextromethorphan; pseudoephedrine). Common drug interactions include urinary tract infection among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Dayquil. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,236 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Dayquil?

Dayquil has active ingredients of acetaminophen; dextromethorphan; pseudoephedrine. It is often used in cold symptoms. eHealthMe is studying from 1,815 Dayquil users. Check the latest studies of Dayquil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

41 people who take Amoxicillin and Dayquil together, and have interactions are studied.

Amoxicillin and Dayquil drug interactions.

What are the common drug interactions of Amoxicillin and Dayquil, by gender? *:

female:

Urinary tract infection
Anxiety
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infusion site pain
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Upper respiratory tract infection
Dysmenorrhoea (painful menstruation)
Chronic kidney disease
Completed suicide (act of taking one's own life)
Hordeolum (small collection of pus (abscess) on the eyelid)

male:

Pyrexia (fever)
Blood bicarbonate increased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypospadias (an abnormal condition in males in which the urethra opens on the under surface of the penis)
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
Injury
Intercostal retraction (inward movement of the muscles between the ribs as a result of reduced pressure in the chest cavity)
Lung disorder (lung disease)
Nasal flaring (nostrils widen while a person is breathing)
Oxygen saturation decreased

What are the common drug interactions of Amoxicillin and Dayquil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug administration error
Erythema (redness of the skin)
Ocular hyperaemia (an abnormally large amount of blood in eye)
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Skin burning sensation

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Drug ineffective
Gamma-glutamyltransferase increased
Heart rate increased
Malaise (a feeling of general discomfort or uneasiness)
Overdose

40-49:

Dysmenorrhoea (painful menstruation)
Completed suicide (act of taking one's own life)
Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pulmonary embolism (blockage of the main artery of the lung)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Vomiting

50-59:

Anxiety
Chronic kidney disease
Abdominal pain
Diarrhoea
Overdose

60+:

Chronic kidney disease
Urinary tract infection
Breast cancer female
Colitis (inflammation of colon)
Disease recurrence
Partial seizures (seizures which affect only a part of the brain at onset)
Pneumonia
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infusion site pain
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the existing conditions these people have? *

Depression: 11 people, 26.83%
Pain: 10 people, 24.39%
Multiple Allergies (allergy to multiple agents): 8 people, 19.51%
Nasopharyngitis (inflammation of the nasopharynx): 8 people, 19.51%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 17.07%
Insomnia (sleeplessness): 6 people, 14.63%
Stress And Anxiety: 6 people, 14.63%
Nausea (feeling of having an urge to vomit): 6 people, 14.63%
Cough: 5 people, 12.20%
Headache (pain in head): 5 people, 12.20%

* Approximation only. Some reports may have incomplete information.

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