Amoxicillin and Epiduo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Epiduo (adapalene; benzoyl peroxide). Common drug interactions include anxiety among females and lower respiratory tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Epiduo. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Epiduo?

Epiduo has active ingredients of adapalene; benzoyl peroxide. It is often used in acne. eHealthMe is studying from 1,581 Epiduo users. Check the latest studies of Epiduo.

On Aug, 06, 2026

32 people who take Amoxicillin and Epiduo together, and have interactions are studied.

Amoxicillin and Epiduo drug interactions.

What are the common drug interactions of Amoxicillin and Epiduo, by gender? *:

female:

Anxiety
Ear pain
Hypoacusis (loss of hearing)
Muscle spasms (muscle contraction)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Nasopharyngitis (inflammation of the nasopharynx)
Road traffic accident
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Upper respiratory tract infection
Weight increased

male:

Lower respiratory tract infection
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain
Pneumonia
Pyrexia (fever)
Renal impairment (severely reduced kidney function)
Abdominal pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Amoxicillin and Epiduo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Constipation
Cough
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Oropharyngeal pain
Pyrexia (fever)
Upper respiratory tract infection
Abdominal pain
Anxiety
Arthralgia (joint pain)

20-29:

Pneumonia

30-39:

Headache (pain in head)

40-49:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Nephritis (inflammation of the nephrons in the kidneys)
Upper respiratory tract infection
Swollen tongue (swelling of tongue)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Hyperthyroidism (over activity of the thyroid gland)
Lower respiratory tract infection

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood creatinine increased
Chronic kidney disease
Emotional distress
Pain
Renal impairment (severely reduced kidney function)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 43.75%
High Blood Pressure: 11 people, 34.38%
Productive Cough: 10 people, 31.25%
Pain: 10 people, 31.25%
Folliculitis (infection of hair root): 10 people, 31.25%
Fever: 10 people, 31.25%
Malignant Melanoma (skin cancer rises from melancytes): 8 people, 25.00%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 5 people, 15.62%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 15.62%
Drowsiness: 4 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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