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Amoxicillin and Kadian drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Kadian (morphine sulfate). Common drug interactions include bronchitis among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Kadian. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Kadian?

Kadian has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 23,045 Kadian users. Check the latest studies of Kadian.

On Jul, 31, 2026

50 people who take Amoxicillin and Kadian together, and have interactions are studied.

Amoxicillin and Kadian drug interactions.

What are the common drug interactions of Amoxicillin and Kadian, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Calcinosis (calcium deposits in any soft tissue)
  3. Cardiac disorder
  4. Decreased interest
  5. Fatigue (feeling of tiredness)
  6. Fistula discharge (discharge from abnormal passage of structure/organ)
  7. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  8. General physical health deterioration (weak health status)
  9. Hip arthroplasty
  10. Impaired healing

male:

  1. Renal failure (kidney dysfunction)
  2. Anxiety
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Decreased appetite
  5. Hand fracture
  6. Abscess (pus)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Dyspnoea (difficult or laboured respiration)
  10. Emotional distress

What are the common drug interactions of Amoxicillin and Kadian, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Hand fracture
  2. Rib fracture
  3. Bone density decreased
  4. Foot fracture
  5. Multiple fractures
  6. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Renal failure (kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)
  10. Gait disturbance

40-49:

  1. Malignant neoplasm progression (cancer tumour came back)
  2. Mastication disorder (disease of chewing food)
  3. Metastases to liver (cancer spreads to liver)
  4. Metastases to mouth (cancer spreads to mouth)
  5. Osteonecrosis (death of bone)
  6. Pain in jaw
  7. Tooth extraction
  8. Agitation (state of anxiety or nervous excitement)
  9. Alcohol withdrawal syndrome
  10. Alcoholism (problems with alcohol)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Decreased appetite
  5. Drug dependence
  6. Drug tolerance increased
  7. Insomnia (sleeplessness)
  8. Irritability
  9. Learning disability (difficulty in learning)
  10. Lethargy (tiredness)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Pain in extremity
  4. Pneumonia
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Drug hypersensitivity
  7. Decreased appetite
  8. Dehydration (dryness resulting from the removal of water)
  9. Heart rate decreased
  10. Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 26.00%
  2. High Blood Pressure: 12 people, 24.00%
  3. Immunodeficiency: 8 people, 16.00%
  4. Hiv Infection: 7 people, 14.00%
  5. Stress And Anxiety: 6 people, 12.00%
  6. Depression: 6 people, 12.00%
  7. High Blood Cholesterol: 6 people, 12.00%
  8. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 10.00%
  9. Chest Pain: 5 people, 10.00%
  10. Diabetes: 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxicillin and Kadian?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amoxicillin and Kadian:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Kadian:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Kadian and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin and morphine sulfate (the active ingredients of Amoxicillin and Kadian, respectively), and Amoxicillin and Kadian (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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