Amoxicillin and Pacerone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Pacerone (amiodarone hydrochloride). Common drug interactions include abdominal pain upper among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Pacerone. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Pacerone?

Pacerone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,814 Pacerone users. Check the latest studies of Pacerone.



On Jul, 31, 2026

68 people who take Amoxicillin and Pacerone together, and have interactions are studied.

Amoxicillin and Pacerone drug interactions.

What are the common drug interactions of Amoxicillin and Pacerone, by gender? *:

female:

  1. Abdominal pain upper
  2. Acute myocardial infarction (acute heart attack)
  3. Chest pain
  4. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
  5. Enuresis (repeated inability to control urination)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  8. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  9. Fall
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

  1. Chronic kidney disease
  2. Cardiac failure congestive
  3. Injury
  4. Cardiomyopathy (weakening of the heart muscle)
  5. Diarrhoea
  6. Oropharyngeal pain
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  9. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  10. Blood glucose increased

What are the common drug interactions of Amoxicillin and Pacerone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain
  2. Abnormal behaviour
  3. Acute respiratory failure
  4. Affect lability (emotional incontinence)
  5. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  6. Anxiety
  7. Balance disorder
  8. Brain injury
  9. Cardiac arrest
  10. Cardioactive drug level increased

20-29:

n/a

30-39:

  1. Cardiac arrest
  2. Cardiogenic shock (inadequate circulation of blood)
  3. Chronic kidney disease
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Renal tubular necrosis (death of kidney tubules)
  7. Right ventricular failure (right half of the heart fails to work)
  8. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

  1. Brain natriuretic peptide increased
  2. Cholecystitis acute (rapid infection of gallbladder)
  3. Exercise tolerance decreased
  4. Pulmonary arterial pressure increased
  5. Pulmonary congestion (congestion in the lungs)
  6. Renal failure acute (rapid kidney dysfunction)
  7. Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
  8. Atrioventricular block first degree (heart block first degree)
  9. Cardiac failure
  10. Cardiac failure congestive

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Gastric haemorrhage (bleeding stomach)
  5. Haemorrhagic anaemia (anaemia due to excessive bleeding)
  6. Muscle spasms (muscle contraction)

60+:

  1. Pain
  2. Anaemia (lack of blood)
  3. Fall
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Acute myocardial infarction (acute heart attack)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Insomnia (sleeplessness)
  8. Multiple injuries
  9. Chest discomfort
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

  1. Cardiac Disorder: 15 people, 22.06%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 22.06%
  3. High Blood Cholesterol: 12 people, 17.65%
  4. Pain: 10 people, 14.71%
  5. High Blood Pressure: 9 people, 13.24%
  6. Cardiac Failure Congestive: 8 people, 11.76%
  7. Depression: 7 people, 10.29%
  8. Diabetes: 7 people, 10.29%
  9. Glaucoma (increased fluid pressure in the eye with vision loss): 6 people, 8.82%
  10. Fluid Retention (an abnormal accumulation of fluid in the blood): 6 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amoxicillin and Pacerone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pacerone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pacerone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin and amiodarone hydrochloride (the active ingredients of Amoxicillin and Pacerone, respectively), and Amoxicillin and Pacerone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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