Amoxicillin and Prinzide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Prinzide (hydrochlorothiazide; lisinopril). Common drug interactions include red blood cell count decreased among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Prinzide. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Prinzide?

Prinzide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 2,218 Prinzide users. Check the latest studies of Prinzide.

On Jul, 14, 2026

31 people who take Amoxicillin and Prinzide together, and have interactions are studied.

Amoxicillin and Prinzide drug interactions.

What are the common drug interactions of Amoxicillin and Prinzide, by gender? *:

female:

Red blood cell count decreased
Serum ferritin increased
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Shoplifting
Skin lesion
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Suicidal ideation
Suicide attempt
Syncope (loss of consciousness with an inability to maintain postural tone)
Tachyphrenia (abnormally rapid mental activity)

male:

Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Leukopenia (less number of white blood cells in blood)
Pleural effusion (water on the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Splenomegaly (enlargement of spleen)
Weight decreased
Abasia (inability to walk)

What are the common drug interactions of Amoxicillin and Prinzide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Angioedema (rapid swelling of the dermis)
Drug hypersensitivity
Lip swelling
Swollen tongue (swelling of tongue)
Abscess limb (limb infection)
Anxiety
Asthenia (weakness)
Blood albumin decreased
Blood chloride decreased
Blood creatine phosphokinase increased

40-49:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Bipolar disorder (mood disorder)
Cardiomegaly (increased size of heart than normal)
Coronary artery stenosis (narrowing of coronary artery)
Fall
Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
Psychotic disorder
Pulmonary embolism (blockage of the main artery of the lung)
Tongue disorder (disease of tongue)
Type 2 diabetes mellitus

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Application site haematoma (collection of blood outside the blood vessels at application site)
Haemolytic anaemia (anaemia due to haemolysis)
Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Abasia (inability to walk)
Accidental exposure
Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Pleural effusion (water on the lungs)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Splenomegaly (enlargement of spleen)
Weight decreased
Alopecia (absence of hair from areas of the body)
Psychological trauma
Muscle spasms (muscle contraction)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 35.48%
Blood Pressure Abnormal: 5 people, 16.13%
Pain: 5 people, 16.13%
Sleep Disorder: 4 people, 12.90%
Motion Sickness (travel sickness): 4 people, 12.90%
Stress And Anxiety: 3 people, 9.68%
Insomnia (sleeplessness): 3 people, 9.68%
Indigestion: 2 people, 6.45%
Cough: 2 people, 6.45%
Hepatitis C: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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