Amoxicillin and Zyflo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxicillin (amoxicillin) and Zyflo (zileuton). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Amoxicillin and Zyflo. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

What is Zyflo?

Zyflo has active ingredients of zileuton. eHealthMe is studying from 1,004 Zyflo users. Check the latest studies of Zyflo.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

18 people who take Amoxicillin and Zyflo together, and have interactions are studied.

Amoxicillin and Zyflo drug interactions.

What are the common drug interactions of Amoxicillin and Zyflo, by gender? *:

female:

Fatigue (feeling of tiredness)
Asthma
Anxiety
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Asthenia (weakness)
Blood calcium decreased
Blood pressure decreased
Cardiac arrest
Cardiac failure congestive

male:

n/a

What are the common drug interactions of Amoxicillin and Zyflo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Asthma
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)

50-59:

Anoxic encephalopathy (brain damage due to lack of oxygen)
Arrhythmia (irregular heartbeat)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Rectal haemorrhage (bleeding from anus)
Renal failure chronic (long lasting kidney dysfunction)
Vomiting
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

n/a

What are the existing conditions these people have? *

Asthma: 8 people, 44.44%
Breast Cancer Female: 3 people, 16.67%
Pain: 2 people, 11.11%
Immunodeficiency Common Variable: 2 people, 11.11%
Hiv Infection: 2 people, 11.11%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 1 person, 5.56%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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