Amoxil and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amoxil (amoxicillin) and Compazine (prochlorperazine maleate). Common drug interactions include decreased appetite among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Amoxil and Compazine. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Amoxil?

Amoxil has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 3,641 Amoxil users. Check the latest studies of Amoxil.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.



On Jul, 15, 2026

39 people who take Amoxil and Compazine together, and have interactions are studied.

Amoxil and Compazine drug interactions.

What are the common drug interactions of Amoxil and Compazine, by gender? *:

female:

  1. Decreased appetite
  2. Dehydration (dryness resulting from the removal of water)
  3. Blood bilirubin increased
  4. Haemoglobin decreased
  5. Hyperglycaemia (high blood sugar)
  6. Diarrhoea
  7. Alanine aminotransferase increased
  8. Aspartate aminotransferase increased
  9. Blood corticotrophin decreased
  10. Drug ineffective

male:

  1. Anxiety
  2. Arthropathy
  3. Cataract (clouding of the lens inside the eye)
  4. Cellulitis (infection under the skin)
  5. Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Conjunctivitis (pink eye)
  8. Cough
  9. Decreased appetite
  10. Dental caries

What are the common drug interactions of Amoxil and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Pain
  3. Abdominal pain
  4. Decreased appetite
  5. Dehydration (dryness resulting from the removal of water)
  6. Dizziness
  7. Blood bilirubin increased
  8. Hyperglycaemia (high blood sugar)
  9. Alanine aminotransferase increased
  10. Aspartate aminotransferase increased

20-29:

n/a

30-39:

n/a

40-49:

  1. Dysmenorrhoea (painful menstruation)
  2. Emotional distress
  3. Eye inflammation
  4. Facial pain
  5. Fatigue (feeling of tiredness)
  6. Foot deformity (functional disability of foot)
  7. Foot fracture
  8. Gait disturbance
  9. Gastric ulcer (stomach ulcer)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

  1. Drug ineffective
  2. Abdominal discomfort
  3. Abdominal pain upper
  4. Adverse drug reaction
  5. Anaemia (lack of blood)
  6. Anxiety
  7. Blood pressure increased
  8. Chills (felling of cold)
  9. Constipation
  10. Depressed mood

60+:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  3. Asthenia (weakness)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Arthropathy
  8. Depression
  9. Diarrhoea
  10. Disease progression

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 18 people, 46.15%
  2. Pain: 17 people, 43.59%
  3. Multiple Myeloma (cancer of the plasma cells): 7 people, 17.95%
  4. Wheezing (a high-pitched whistling sound made while you breath): 5 people, 12.82%
  5. Dyspnea (difficult or laboured breathing): 5 people, 12.82%
  6. Stress And Anxiety: 5 people, 12.82%
  7. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 12.82%
  8. Insomnia (sleeplessness): 4 people, 10.26%
  9. Cough: 3 people, 7.69%
  10. Depression: 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Amoxil and Compazine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amoxil and Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amoxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Compazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin and prochlorperazine maleate (the active ingredients of Amoxil and Compazine, respectively), and Amoxil and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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