Amphetamine and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amphetamine (amphetamine) and Abilify (aripiprazole). Common drug interactions include skin lesion among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Amphetamine and Abilify. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Amphetamine?

Amphetamine has active ingredients of amphetamine. eHealthMe is studying from 980 Amphetamine users. Check the latest studies of Amphetamine.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.



On Jul, 13, 2026

11 people who take Amphetamine and Abilify together, and have interactions are studied.

Amphetamine and Abilify drug interactions.

What are the common drug interactions of Amphetamine and Abilify, by gender? *:

female:

  1. Skin lesion
  2. Social problem
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Spinal fracture (fracture in one of vertebrae)
  5. Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
  6. Surgery
  7. Tardive dyskinesia (a disorder that involves involuntary movements)
  8. Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
  9. Tenderness (pain or discomfort when an affected area is touched)
  10. Tooth erosion (dissolving teeth)

male:

  1. Aggression
  2. Agitation (state of anxiety or nervous excitement)
  3. Hallucination, auditory (perceiving sounds without auditory stimulus)
  4. Hallucination, visual (seeing things that aren't there)
  5. Headache (pain in head)
  6. Jaw fracture
  7. Neck pain
  8. Psychological trauma
  9. Renal failure (kidney dysfunction)
  10. Renal injury (kidney injury)

What are the common drug interactions of Amphetamine and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Hallucination, auditory (perceiving sounds without auditory stimulus)
  3. Hallucination, visual (seeing things that aren't there)
  4. Headache (pain in head)
  5. Psychological trauma
  6. Substance-induced psychotic disorder
  7. Weight increased

20-29:

  1. Dental caries
  2. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  3. Tooth erosion (dissolving teeth)
  4. Tooth loss

30-39:

  1. Antinuclear antibody positive
  2. Arthralgia (joint pain)
  3. Back pain
  4. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  5. Blood pressure increased
  6. Chest pain
  7. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  8. Family stress
  9. Fatigue (feeling of tiredness)
  10. Fibromyalgia (a long-term condition which causes pain all over the body)

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)

60+:

  1. Fatigue (feeling of tiredness)
  2. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  3. Impaired work ability
  4. Injection site pain
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  7. Weight increased

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 27.27%
  3. Drowsiness: 3 people, 27.27%
  4. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 18.18%
  5. Pain: 2 people, 18.18%
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus): 1 person, 9.09%
  7. Back Pain: 1 person, 9.09%
  8. Bipolar Disorder (mood disorder): 1 person, 9.09%
  9. Cardiac Disorder: 1 person, 9.09%
  10. Cystic Fibrosis (disease of the secretary glands): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Amphetamine and Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Amphetamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amphetamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amphetamine and aripiprazole (the active ingredients of Amphetamine and Abilify, respectively), and Amphetamine and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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