Amrix and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Amrix (cyclobenzaprine hydrochloride) and Digoxin (digoxin). Common drug interactions include chest pain among females and injury among males.

The phase IV clinical study analyzes what interactions people have when they take Amrix and Digoxin. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Amrix?

Amrix has active ingredients of cyclobenzaprine hydrochloride. It is often used in back pain. eHealthMe is studying from 1,130 Amrix users. Check the latest studies of Amrix.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Jul, 17, 2026

29 people who take Amrix and Digoxin together, and have interactions are studied.

What are the common drug interactions of Amrix and Digoxin, by gender? *:

female:

Chest pain
Hypertriglyceridaemia (excess of triglycerides in the blood)
Urinary tract infection
Abdominal pain
Angina pectoris (chest pain due to ischemia of the heart muscle)
Cardiomyopathy (weakening of the heart muscle)
Multiple injuries
Palpitations (feelings or sensations that your heart is pounding or racing)
Depression
Abdominal adhesions (inflammation of abdomen)

male:

Injury
Anxiety
Haematuria (presence of blood in urine)
Pain in extremity
Pleural fibrosis (formation of fibrous tissue in lung)
Rales (an abnormal respiratory sound characterized by fine crackles)
Splenomegaly (enlargement of spleen)
Weight increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Amrix and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Injury
Cough
Dyspnoea (difficult or laboured respiration)
Pain in extremity
Haematuria (presence of blood in urine)
Pain
Abdominal distension
Anxiety
Pleural fibrosis (formation of fibrous tissue in lung)
Rales (an abnormal respiratory sound characterized by fine crackles)

40-49:

n/a

50-59:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Cardiac failure congestive
Depression
Headache (pain in head)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Renal failure acute (rapid kidney dysfunction)
Arteriosclerosis (thickening and hardening of arteries)
Dyspnoea (difficult or laboured respiration)

60+:

Injury
Dyspnoea (difficult or laboured respiration)
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Coronary artery stenosis (narrowing of coronary artery)
Culture positive
Dilatation ventricular
Heart rate increased
Intervertebral disc disorder (spinal disc disorder)
Left ventricular end-diastolic pressure increased
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Heart Rate Increased: 4 people, 13.79%
Cardiac Disorder: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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