Anafranil and Clopra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anafranil (clomipramine hydrochloride) and Clopra (metoclopramide hydrochloride). Common drug interactions include coma among females and metastases to liver among males.

The phase IV clinical study analyzes what interactions people have when they take Anafranil and Clopra. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Anafranil?

Anafranil has active ingredients of clomipramine hydrochloride. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 6,304 Anafranil users. Check the latest studies of Anafranil.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

On Aug, 06, 2026

17 people who take Anafranil and Clopra together, and have interactions are studied.

What are the common drug interactions of Anafranil and Clopra, by gender? *:

female:

Coma (state of unconsciousness lasting more than six hours)
Erythema (redness of the skin)
Gamma-glutamyltransferase increased
Hallucination (an experience involving the perception of something not present)
Hepatic failure (liver failure)
Influenza
Methicillin-resistant staphylococcal aureus infection
Nikolsky's sign
Pain
Pneumonia

male:

Metastases to liver (cancer spreads to liver)
Metastases to lymph nodes (cancer spreads to lymph node)
Pancreatic carcinoma recurrent (pancreatic cancer - recurrent)
Pancreatitis (inflammation of pancreas)
Rash erythematous (redness of the skin)

What are the common drug interactions of Anafranil and Clopra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abasia (inability to walk)
Arthralgia (joint pain)
Iron overload
Serum ferritin increased
Transaminases increased
Vision blurred

40-49:

Fatigue (feeling of tiredness)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Hepatic failure (liver failure)
Constipation

50-59:

Coma (state of unconsciousness lasting more than six hours)
Hallucination (an experience involving the perception of something not present)
Influenza
Methicillin-resistant staphylococcal aureus infection
Pneumonia
Drug ineffective
Feeling drunk
Gait abnormal
Metastases to liver (cancer spreads to liver)
Metastases to lymph nodes (cancer spreads to lymph node)

60+:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Erythema (redness of the skin)
Dyspnoea (difficult or laboured respiration)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Mucosal inflammation (infection of mucous membrane)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Non-small cell lung cancer (type of epithelial lung cancer)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

What are the existing conditions these people have? *

Pain: 3 people, 17.65%
Breast Cancer: 3 people, 17.65%
Nausea (feeling of having an urge to vomit): 3 people, 17.65%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 17.65%
Gastric Ulcer (stomach ulcer): 3 people, 17.65%
Klebsiella Infection: 2 people, 11.76%
Hypersensitivity: 2 people, 11.76%
Diarrhea: 2 people, 11.76%
Migraine (headache): 2 people, 11.76%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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