Anaprox and Lisinopril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Anaprox (naproxen sodium) and Lisinopril (lisinopril). Common drug interactions include depression among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Anaprox and Lisinopril. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.
What is Anaprox?
Anaprox has active ingredients of naproxen sodium. eHealthMe is studying from 1,370 Anaprox users. Check the latest studies of Anaprox.
What is Lisinopril?
Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.
69 people who take Anaprox and Lisinopril together, and have interactions are studied.

What are the common drug interactions of Anaprox and Lisinopril, by gender? *:
female:
- Depression
- Fatigue (feeling of tiredness)
- Foot fracture
- Chest pain
- Abdominal pain upper
- Injury
- Pain
- Arthropathy
- Emotional distress
- Hypotension (abnormally low blood pressure)
male:
- Depression
- Arthralgia (joint pain)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
- Constipation
- Decreased appetite
- Emotional distress
- Gastric cancer recurrent (repeat stomach cancer)
- Gastric ulcer (stomach ulcer)
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
What are the common drug interactions of Anaprox and Lisinopril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Injury
- Pain
- Anxiety
- Emotional distress
- Blood triglycerides increased
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hyperhomocysteinaemia (abnormally high level of homocysteine in the blood)
- Neuropathy peripheral (surface nerve damage)
- Type 2 diabetes mellitus
30-39:
- Abdominal pain upper
- Cholecystitis chronic (long lasting infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Cholesterosis (abnormal deposition of cholesterol in tissues)
- Diarrhoea
- Abscess (pus)
- Arthralgia (joint pain)
- Back pain
- Cardiomyopathy (weakening of the heart muscle)
- Cyst (a closed sac)
40-49:
- Pain in extremity
- Cardiac arrest
- Chest pain
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Pulmonary embolism (blockage of the main artery of the lung)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Anxiety
- Atrioventricular block first degree (heart block first degree)
- Back pain
50-59:
- Pneumonia
- Rectal haemorrhage (bleeding from anus)
- Scoliosis (a medical condition in which a person's spine is curved from side to side)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Thrombocytopenia (decrease of platelets in blood)
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypotension (abnormally low blood pressure)
- Metastases to bone (cancer spreads to bone)
- Pancreatic carcinoma (pancreatic cancer)
60+:
- Acute respiratory failure
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Pancreatic phlegmon (diffuse inflammation of the soft or connective tissue due to infection of pancreas)
- Pancreatitis (inflammation of pancreas)
- Anaemia (lack of blood)
- Intussusception
- Rectal haemorrhage (bleeding from anus)
- Abdominal abscess (collection of pus in abdomen)
- Abdominal mass (localized enlargement or swelling in the human abdomen)
- Abdominal pain lower
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 18.84%
- Pain: 12 people, 17.39%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 11.59%
- Seasonal Affective Disorder (a type of depression that occurs at a certain time of the year, usually in the winter): 5 people, 7.25%
- Menstruation Irregular: 5 people, 7.25%
- Headache (pain in head): 5 people, 7.25%
- Ovarian Cysts (fluid filled sacs of the ovary): 4 people, 5.80%
- Muscle Spasms (muscle contraction): 4 people, 5.80%
- Migraine (headache): 4 people, 5.80%
- Infection: 4 people, 5.80%
* Approximation only. Some reports may have incomplete information.
Do you take Anaprox and Lisinopril?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Anaprox (1,370 reports)
- Lisinopril (358,654 reports)
Browse all drug interactions of Anaprox and Lisinopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Anaprox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lisinopril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Anaprox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lisinopril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
- Dobrosavljevi? Vukojevi? D, Stojkovi? Filipovi? J, Sjerobabin M, Vukovi? J, Vesi? S, "Lisinopril-induced pemphigus foliaceus in a patient with diabetes mellitus and Kaposi-Juliusberg varicelliform eruption", Serbian Journal of Dermatology and Venerology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on naproxen sodium and lisinopril (the active ingredients of Anaprox and Lisinopril, respectively), and Anaprox and Lisinopril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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