Anaprox and Pantoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anaprox (naproxen sodium) and Pantoprazole (pantoprazole sodium). Common drug interactions include myocardial infarction among females and anal abscess among males.

The phase IV clinical study analyzes what interactions people have when they take Anaprox and Pantoprazole. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Anaprox?

Anaprox has active ingredients of naproxen sodium. eHealthMe is studying from 1,370 Anaprox users. Check the latest studies of Anaprox.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.



On Jul, 15, 2026

40 people who take Anaprox and Pantoprazole together, and have interactions are studied.

Anaprox and Pantoprazole drug interactions.

What are the common drug interactions of Anaprox and Pantoprazole, by gender? *:

female:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Drug hypersensitivity
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Venous occlusion (the blocking of venous return)
  5. Arthropathy
  6. Dysphonia (speech disorder attributable to a disorder of phonation)
  7. Nausea (feeling of having an urge to vomit)
  8. Arthralgia (joint pain)
  9. Blood pressure increased
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

  1. Anal abscess
  2. Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
  3. Drug ineffective
  4. Drug intolerance (drug sensitivity)
  5. Foot fracture
  6. Haemorrhage (bleeding)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Rash
  10. Renal cyst (kidney cyst)

What are the common drug interactions of Anaprox and Pantoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Nervousness
  4. Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

n/a

50-59:

  1. Drug hypersensitivity
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Arthralgia (joint pain)
  4. Foot fracture
  5. Abscess rupture (pus release from the point of abscess)
  6. Arthropathy
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Crying
  9. Drug ineffective
  10. Drug intolerance (drug sensitivity)

60+:

  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Venous occlusion (the blocking of venous return)
  3. Headache (pain in head)
  4. Influenza
  5. Joint injury
  6. Knee arthroplasty
  7. Nausea (feeling of having an urge to vomit)
  8. Sinusitis (inflammation of sinus)
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Rash

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 47.50%
  2. Seasonal Affective Disorder (a type of depression that occurs at a certain time of the year, usually in the winter): 5 people, 12.50%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 10.00%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 10.00%
  5. High Blood Pressure: 4 people, 10.00%
  6. High Blood Cholesterol: 4 people, 10.00%
  7. Gastric Disorder (disease of stomach): 4 people, 10.00%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.50%
  9. Gastritis (inflammation of stomach): 3 people, 7.50%
  10. Depression: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Anaprox and Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Anaprox:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pantoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Anaprox and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pantoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on naproxen sodium and pantoprazole sodium (the active ingredients of Anaprox and Pantoprazole, respectively), and Anaprox and Pantoprazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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