Androgel and Edurant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Androgel (testosterone) and Edurant (rilpivirine hydrochloride). Common drug interactions include emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Androgel and Edurant. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Androgel?

Androgel has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 25,763 Androgel users. Check the latest studies of Androgel.

What is Edurant?

Edurant has active ingredients of rilpivirine hydrochloride. eHealthMe is studying from 2,238 Edurant users. Check the latest studies of Edurant.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

14 people who take Androgel and Edurant together, and have interactions are studied.

What are the common drug interactions of Androgel and Edurant, by gender? *:

female:

n/a

male:

Emotional distress
Pain
Tooth loss
Femoral neck fracture (neck of femur bone fracture)
Multiple fractures
Osteomalacia (softening of the bones due to a lack of vitamin d)
Osteoporotic fracture (fracture due to weak bone)
Back pain
Blood creatinine increased
Insomnia (sleeplessness)

What are the common drug interactions of Androgel and Edurant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Back pain
Blood creatinine increased
Depression
Emotional distress
Insomnia (sleeplessness)
Nocturia (the need to get up in the night to urinate)
Pain

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Blood triglycerides increased
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Back pain

50-59:

Osteoporosis (bones weak and more likely to break)
Bone density decreased
Emotional distress
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Depression
Multiple fractures

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tooth loss
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Hiv Infection: 14 people, 100.00%
Peripheral Swelling: 2 people, 14.29%
Depression: 2 people, 14.29%
Rickets (softening of bones): 1 person, 7.14%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
Infection: 1 person, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.14%
Hypersensitivity: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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