Androgel and Prolia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Androgel (testosterone) and Prolia (denosumab). Common drug interactions include retinal detachment among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Androgel and Prolia. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Androgel?

Androgel has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 25,763 Androgel users. Check the latest studies of Androgel.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

On Jul, 20, 2026

41 people who take Androgel and Prolia together, and have interactions are studied.

What are the common drug interactions of Androgel and Prolia, by gender? *:

female:

Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)

male:

Abdominal distension
Speech disorder
Delirium (wild excitement)
Diarrhoea
Skin disorder (skin disease)
Stupor (lack of critical cognitive function and level of consciousness)
Urine output decreased
Consciousness fluctuating
Arthralgia (joint pain)
Pain in extremity

What are the common drug interactions of Androgel and Prolia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)

40-49:

Cystic fibrosis (disease of the secretary glands)
Pertussis (whooping cough: a disease of the respiratory mucous membrane)
Pneumonia

50-59:

Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Neuropathy peripheral (surface nerve damage)
Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
Pain in extremity
Peripheral swelling
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pyrexia (fever)
Restless legs syndrome (a powerful urge to move your legs)

60+:

Abdominal distension
Speech disorder
Diarrhoea
Skin disorder (skin disease)
Stupor (lack of critical cognitive function and level of consciousness)
Urine output decreased
Consciousness fluctuating
Salivary hypersecretion (excess saliva secretion)
Cold sweat
Dementia (madness)

What are the existing conditions these people have? *

Parkinson's Disease: 9 people, 21.95%
Rash - Child Under 2 Years: 8 people, 19.51%
Constipation: 8 people, 19.51%
Dementia (madness): 7 people, 17.07%
Enlarged Prostate: 7 people, 17.07%
Sleep Disorder: 7 people, 17.07%
Skin Disorder (skin disease): 6 people, 14.63%
Psychotic Disorder: 6 people, 14.63%
Insomnia (sleeplessness): 6 people, 14.63%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.20%

* Approximation only. Some reports may have incomplete information.

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