Anectine and Benadryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Anectine (succinylcholine chloride) and Benadryl (diphenhydramine hydrochloride). Common drug interactions include rales among females and epistaxis among males.

The phase IV clinical study analyzes what interactions people have when they take Anectine and Benadryl. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Anectine?

Anectine has active ingredients of succinylcholine chloride. eHealthMe is studying from 287 Anectine users. Check the latest studies of Anectine.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,954 Benadryl users. Check the latest studies of Benadryl.

On Jul, 20, 2026

17 people who take Anectine and Benadryl together, and have interactions are studied.

Anectine and Benadryl drug interactions.

What are the common drug interactions of Anectine and Benadryl, by gender? *:

female:

Rales (an abnormal respiratory sound characterized by fine crackles)
Renal failure acute (rapid kidney dysfunction)
Retinal oedema (excl papilloedema) (optic disc swelling with retina swelling)
Rigors (an episode of shaking or exaggerated shivering)
Secondary anaemia (anaemia due to a disease condition)
Sinusitis chronic (long lasting infection of sinus)
Skin discolouration (change of skin colour)
Spleen congestion (overloaded spleen)
Sputum expectoration difficult (difficult removing of sputum)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

Epistaxis (bleed from the nose)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Disability
Failure to thrive (inadequate weight gain and physical growth in children)
Febrile neutropenia (fever with reduced white blood cells)
Injury
Renal failure (kidney dysfunction)
Respiratory distress (difficulty in breathing)
Sinusitis fungal (fungal infection of sinus)
Hypoxia (low oxygen in tissues)

What are the common drug interactions of Anectine and Benadryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Epistaxis (bleed from the nose)
Sinusitis (inflammation of sinus)
Febrile neutropenia (fever with reduced white blood cells)
Respiratory distress (difficulty in breathing)
Sinusitis fungal (fungal infection of sinus)

10-19:

n/a

20-29:

Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Cough
Diabetic complication
Diabetic nephropathy (diabetic kidney disease)
Difficulty in walking
Dizziness (excl vertigo)
Dyspnoea (difficult or laboured respiration)
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Eye swelling
Face oedema (swelling of face)

30-39:

n/a

40-49:

Abdominal distension
Abdominal pain
Device dislocation
Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Lymphocyte count decreased
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Migraine (headache)
Uterine haemorrhage (uterine bleeding)
Haemangioma of skin (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)

50-59:

Disability
Failure to thrive (inadequate weight gain and physical growth in children)
Injury
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Angioimmunoblastic t-cell lymphoma stage iv (mature t-cell cancer of the blood or lymph vessel-stage iv)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease

60+:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hypoxia (low oxygen in tissues)
Ankle fracture
Blood bilirubin increased
Blood glucose increased
Blood urea increased
Blood uric acid increased

What are the existing conditions these people have? *

Pain: 9 people, 52.94%
Nausea (feeling of having an urge to vomit): 6 people, 35.29%
Depression: 4 people, 23.53%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 17.65%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 17.65%
Hypokalemia (low potassium): 3 people, 17.65%
Migraine Without Aura (headache without neurological problems): 3 people, 17.65%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
Fever: 3 people, 17.65%
Type 1 Diabetes: 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

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