Antivert and Rocephin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Antivert (meclizine hydrochloride) and Rocephin (ceftriaxone sodium). Common drug interactions include exacerbation of anxiety among females and pulmonary embolism among males.
The phase IV clinical study analyzes what interactions people have when they take Antivert and Rocephin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Antivert?
Antivert has active ingredients of meclizine hydrochloride. It is often used in dizziness. eHealthMe is studying from 4,087 Antivert users. Check the latest studies of Antivert.
What is Rocephin?
Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.
32 people who take Antivert and Rocephin together, and have interactions are studied.

What are the common drug interactions of Antivert and Rocephin, by gender? *:
female:
- Exacerbation of anxiety (increase in the severity of anxiety)
- Fall
- Hypertension (high blood pressure)
- Sedation
- Back pain
- Blood cholesterol increased
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Dysphagia (a condition in which swallowing is difficult or painful)
male:
- Pulmonary embolism (blockage of the main artery of the lung)
- Cardiac failure congestive
- Decreased appetite
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Heart rate irregular
- Oropharyngeal pain
- Pain
- Productive cough
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
What are the common drug interactions of Antivert and Rocephin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Drug dependence
- Anger
- Exacerbation of anxiety (increase in the severity of anxiety)
- Sedation
- Anxiety
- Drug effect decreased
- Hypersomnia (excessive daytime sleepiness (eds))
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Aggression
40-49:
- Dysphagia (a condition in which swallowing is difficult or painful)
- Upper respiratory tract infection
- Abdominal pain upper
- Blindness
- Blood potassium increased
- Blood triglycerides increased
- Cardiomyopathy (weakening of the heart muscle)
- Carotid bruit (sound heard over the carotid artery area during auscultation)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Constipation
50-59:
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Diarrhoea
60+:
- Pulmonary embolism (blockage of the main artery of the lung)
- Cardiac failure congestive
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Troponin increased
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Asthenia (weakness)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Diarrhoea
- Dysuria (painful or difficult urination)
- Gait disturbance
What are the existing conditions these people have? *
- Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 15.62%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 15.62%
- Stress And Anxiety: 4 people, 12.50%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 9.38%
- Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 3 people, 9.38%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.38%
- Diarrhea: 3 people, 9.38%
- Joint Pain: 3 people, 9.38%
- Diabetes: 3 people, 9.38%
- Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 9.38%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Antivert and Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Antivert:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Antivert and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rocephin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on meclizine hydrochloride and ceftriaxone sodium (the active ingredients of Antivert and Rocephin, respectively), and Antivert and Rocephin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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