Aplenzin and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aplenzin (bupropion hydrobromide) and Ambien (zolpidem tartrate). Common drug interactions include balance disorder among females and hepatic enzyme increased among males.

The phase IV clinical study analyzes what interactions people have when they take Aplenzin and Ambien. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Aplenzin?

Aplenzin has active ingredients of bupropion hydrobromide. It is often used in depression. eHealthMe is studying from 396 Aplenzin users. Check the latest studies of Aplenzin.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 26, 2026

14 people who take Aplenzin and Ambien together, and have interactions are studied.

What are the common drug interactions of Aplenzin and Ambien, by gender? *:

female:

Balance disorder
Dyskinesia (abnormality or impairment of voluntary movement)
Gait disturbance
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Attention deficit/hyperactivity disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Burning sensation
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Compulsions (performing an act persistently and repetitively)
Contusion (a type of hematoma of tissue in which capillaries)

male:

Hepatic enzyme increased
Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)

What are the common drug interactions of Aplenzin and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Attention deficit/hyperactivity disorder
Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Crying
Dysstasia (difficulty in standing)
Fatigue (feeling of tiredness)
Feeling of body temperature change
Gastric disorder (disease of stomach)

50-59:

Abnormal dreams
Anxiety
Balance disorder
Crying
Drug ineffective
Dyskinesia (abnormality or impairment of voluntary movement)
Gait disturbance
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Drug ineffective
Dry mouth
Dry throat
Erythema (redness of the skin)
Joint swelling
Swelling face

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 35.71%
Stress And Anxiety: 5 people, 35.71%
Infection: 4 people, 28.57%
Asthma: 4 people, 28.57%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 28.57%
Hypokalemia (low potassium): 3 people, 21.43%
Arrhythmias (irregular heartbeat): 3 people, 21.43%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 21.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 21.43%
Cough: 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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