Aplenzin and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aplenzin (bupropion hydrobromide) and Nexium (esomeprazole magnesium). Common drug interactions include chronic kidney disease among females.

The phase IV clinical study analyzes what interactions people have when they take Aplenzin and Nexium. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Aplenzin?

Aplenzin has active ingredients of bupropion hydrobromide. It is often used in depression. eHealthMe is studying from 396 Aplenzin users. Check the latest studies of Aplenzin.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

On Aug, 05, 2026

13 people who take Aplenzin and Nexium together, and have interactions are studied.

What are the common drug interactions of Aplenzin and Nexium, by gender? *:

female:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hand fracture
Anxiety
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Attention deficit/hyperactivity disorder
Back pain
Blood disorder
Burning sensation
Cholecystitis chronic (long lasting infection of gallbladder)

male:

n/a

What are the common drug interactions of Aplenzin and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Blood disorder
Cholecystitis chronic (long lasting infection of gallbladder)
Depression suicidal (suicide depressive disorder)
Gallbladder disorder
Pain

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
Attention deficit/hyperactivity disorder
Back pain
Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Crying
Feeling of body temperature change
Gastric disorder (disease of stomach)

50-59:

Pancreatitis (inflammation of pancreas)
Clavicle fracture
Foot fracture
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Hand fracture

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Headache (pain in head)
Hypertension (high blood pressure)

What are the existing conditions these people have? *

Insomnia (sleeplessness): 5 people, 38.46%
Stress And Anxiety: 4 people, 30.77%
Asthma: 4 people, 30.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
Infection: 4 people, 30.77%
Arrhythmias (irregular heartbeat): 3 people, 23.08%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 23.08%
Cough: 3 people, 23.08%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 23.08%
High Blood Pressure: 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

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