Apple cider vinegar and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apple cider vinegar (apple cider vinegar) and Profen (ibuprofen). Common drug interactions include dry mouth among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Apple cider vinegar and Profen. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Apple cider vinegar?

Apple cider vinegar has active ingredients of apple cider vinegar. It is often used in weight loss. eHealthMe is studying from 1,380 Apple cider vinegar users. Check the latest studies of Apple cider vinegar.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 10, 2026

90 people who take Apple cider vinegar and Profen together, and have interactions are studied.

Apple cider vinegar and Profen drug interactions.

What are the common drug interactions of Apple Cider Vinegar and Profen, by gender? *:

female:

Dry mouth
Hyperaesthesia
Inflammation
Insomnia (sleeplessness)
Oropharyngeal pain
Pneumonia
Poor venous access
Renal disorder (kidney disease)
Alanine aminotransferase increased
Bipolar disorder (mood disorder)

male:

Insomnia (sleeplessness)
Pain in extremity
Neuropathy peripheral (surface nerve damage)
Nocturia (the need to get up in the night to urinate)
Overdose
Peripheral coldness
Pruritus (severe itching of the skin)
Suicide attempt
Weight increased
Arthralgia (joint pain)

What are the common drug interactions of Apple Cider Vinegar and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Diarrhoea
Dyskinesia (abnormality or impairment of voluntary movement)
Feeling hot
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrointestinal pain
Hypotension (abnormally low blood pressure)
Muscle twitching
Nausea (feeling of having an urge to vomit)
Pallor

20-29:

Abdominal pain upper
Drug ineffective
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)
Rash

30-39:

Injection site bruising
Procedural pain
White blood cell count decreased

40-49:

Arthralgia (joint pain)
Asthma
Breast cancer female
Chills (felling of cold)
Disturbance in attention
Dizziness
Drug hypersensitivity
Dry mouth
Dysphagia (a condition in which swallowing is difficult or painful)
Ear congestion

50-59:

Insomnia (sleeplessness)
Memory impairment
Abdominal hernia
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Haemoglobin decreased
Intervertebral disc protrusion (spinal disc protrusion)
Neuropathy peripheral (surface nerve damage)
Nocturia (the need to get up in the night to urinate)
Pain in extremity
Peripheral coldness

60+:

Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
Fatigue (feeling of tiredness)
Arthralgia (joint pain)
Blood glucose increased
Diarrhoea
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pain in extremity

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 18 people, 20.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 13.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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