Apresoline and Pomalyst drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apresoline (hydralazine hydrochloride) and Pomalyst (pomalidomide). Common drug interactions include fatigue among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Apresoline and Pomalyst. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,475 Apresoline users. Check the latest studies of Apresoline.

What is Pomalyst?

Pomalyst has active ingredients of pomalidomide. eHealthMe is studying from 80,400 Pomalyst users. Check the latest studies of Pomalyst.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

16 people who take Apresoline and Pomalyst together, and have interactions are studied.

Apresoline and Pomalyst drug interactions.

What are the common drug interactions of Apresoline and Pomalyst, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Adverse drug reaction
  3. Cardiac death
  4. Diarrhoea
  5. Drug hypersensitivity
  6. Influenza
  7. Oral herpes (viral infection of mouth)
  8. Pneumonia

male:

  1. Cardiac failure congestive
  2. Pneumonia
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Pathological fracture (broken bone caused by disease)
  5. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  6. Urinary tract infection
  7. Full blood count decreased
  8. Haemoglobin decreased
  9. Influenza
  10. Diarrhoea

What are the common drug interactions of Apresoline and Pomalyst, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Pneumonia
  2. Dyspnoea (difficult or laboured respiration)
  3. Humerus fracture (injury to the upper arm bone)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pathological fracture (broken bone caused by disease)
  6. Plasma cell myeloma (cancer that begins in plasma cells)
  7. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  8. Urinary tract infection
  9. Adverse drug reaction
  10. Drug hypersensitivity

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 16 people, 100.00%
  2. Pain: 2 people, 12.50%
  3. Oedema Peripheral (superficial swelling): 2 people, 12.50%
  4. Constipation: 2 people, 12.50%
  5. Anaemia (lack of blood): 2 people, 12.50%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.25%
  7. High Blood Cholesterol: 1 person, 6.25%
  8. Herpes Zoster: 1 person, 6.25%
  9. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 6.25%
  10. Diarrhea: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Apresoline and Pomalyst?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Apresoline and Pomalyst:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Apresoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pomalyst:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Apresoline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pomalyst and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydralazine hydrochloride and pomalidomide (the active ingredients of Apresoline and Pomalyst, respectively), and Apresoline and Pomalyst (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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