Apriso and Plavix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Apriso (mesalamine) and Plavix (clopidogrel bisulfate). Common drug interactions include asthenia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Apriso and Plavix. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Apriso?

Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

On Jul, 12, 2026

28 people who take Apriso and Plavix together, and have interactions are studied.

What are the common drug interactions of Apriso and Plavix, by gender? *:

female:

Asthenia (weakness)
Chest pain
Malaise (a feeling of general discomfort or uneasiness)
Weight decreased
Adverse drug reaction
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure fluctuation
Cardiac perforation (a hole in heart)
Dehydration (dryness resulting from the removal of water)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

male:

Fatigue (feeling of tiredness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Splenic infarction (tissue damage of spleen)
Abdominal pain
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Chills (felling of cold)
Decreased appetite
Food aversion (we reject certain foods for a reason)
Lethargy (tiredness)
Muscle spasms (muscle contraction)

What are the common drug interactions of Apriso and Plavix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Arthralgia (joint pain)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Irritable bowel syndrome
Psoriasis (immune-mediated disease that affects the skin)
Upper respiratory tract infection

50-59:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Small intestinal obstruction (blockage in small intestine)
Splenic infarction (tissue damage of spleen)
Ageusia (loss of taste functions of the tongue)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Drug ineffective
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)

60+:

Fatigue (feeling of tiredness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure fluctuation
Cardiac perforation (a hole in heart)
Dehydration (dryness resulting from the removal of water)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug ineffective
Haemorrhage (bleeding)
Heart rate irregular

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 57.14%
High Blood Pressure: 6 people, 21.43%
High Blood Cholesterol: 6 people, 21.43%
Pain: 3 people, 10.71%
Irritable Bowel Syndrome: 3 people, 10.71%
Diabetes: 3 people, 10.71%
Depression: 3 people, 10.71%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 10.71%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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