Aptivus and Epivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aptivus (tipranavir) and Epivir (lamivudine). Common drug interactions include hyperparathyroidism secondary among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Aptivus and Epivir. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Aptivus?

Aptivus has active ingredients of tipranavir. eHealthMe is studying from 1,060 Aptivus users. Check the latest studies of Aptivus.

What is Epivir?

Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.

On Aug, 05, 2026

77 people who take Aptivus and Epivir together, and have interactions are studied.

What are the common drug interactions of Aptivus and Epivir, by gender? *:

female:

Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Asthenia (weakness)
Bone density decreased
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Drug resistance (reduction in effectiveness of a drug)
Emotional disorder
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Proteinuria (presence of protein in the urine)

male:

Pain
Emotional distress
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Skin lesion
Urinary tract infection
Drug ineffective
Neoplasm progression (growth of tumour)
Pyrexia (fever)
Osteoporosis (bones weak and more likely to break)
Decreased activity

What are the common drug interactions of Aptivus and Epivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Decreased activity
Emotional distress
Pain
Chronic kidney disease
Depression
Osteoporosis (bones weak and more likely to break)
Fatigue (feeling of tiredness)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Decreased activity
Emotional distress
Pain
Chronic kidney disease
Fatigue (feeling of tiredness)
Quality of life decreased
Bone density decreased
Depression

50-59:

Foot fracture
Gait disturbance
Immune reconstitution syndrome (immune recovery syndrome)
Mobility decreased (ability to move is reduced)
Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
Renal disorder (kidney disease)
Synovial cyst (cyst of joint filled with synovial fluid)
Kaposi's sarcoma (a tumour caused by human herpes virus)
Dysuria (painful or difficult urination)
Immunodeficiency

60+:

Emotional distress
Pain
Blood creatinine increased
Decreased activity
Depression
Hepatitis c
Post-traumatic stress disorder
Renal impairment (severely reduced kidney function)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Osteoporosis (bones weak and more likely to break)

What are the existing conditions these people have? *

Hiv Infection: 66 people, 85.71%
Kaposi's Sarcoma (a tumour caused by human herpes virus): 18 people, 23.38%
Pain: 8 people, 10.39%
High Blood Pressure: 8 people, 10.39%
High Blood Cholesterol: 7 people, 9.09%
Diabetes: 5 people, 6.49%
Asthma: 5 people, 6.49%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 5.19%
Bacterial Infection: 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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