Arava and Buspirone hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arava (leflunomide) and Buspirone hcl (buspirone hydrochloride). Common drug interactions include acute respiratory failure among females.

The phase IV clinical study analyzes what interactions people have when they take Arava and Buspirone hcl. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Buspirone hcl?

Buspirone hcl has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,821 Buspirone hcl users. Check the latest studies of Buspirone hcl.



On Jul, 11, 2026

11 people who take Arava and Buspirone hcl together, and have interactions are studied.

Arava and Buspirone hcl drug interactions.

What are the common drug interactions of Arava and Buspirone Hcl, by gender? *:

female:

  1. Acute respiratory failure
  2. Bronchopneumopathy
  3. Blood sodium decreased
  4. Body mass index increased
  5. Bone cyst
  6. Cerebral disorder (brain disease)
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Cough
  9. Death
  10. Drug ineffective

male:

n/a

What are the common drug interactions of Arava and Buspirone Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Pain

50-59:

  1. Pruritus (severe itching of the skin)
  2. Abdominal pain
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Blood potassium decreased
  5. Blood pressure increased
  6. Blood sodium decreased
  7. Bone cyst
  8. Cerebral disorder (brain disease)
  9. Cough
  10. Drug ineffective

60+:

  1. Acute respiratory failure
  2. Bronchopneumopathy
  3. Oedema (fluid collection in tissue)
  4. Pneumonia
  5. Sinusitis (inflammation of sinus)
  6. Tardive dyskinesia (a disorder that involves involuntary movements)
  7. Tendonitis (a condition that causes pain and swelling of tendons)
  8. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  9. Body mass index increased
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the existing conditions these people have? *

  1. High Blood Pressure: 2 people, 18.18%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 9.09%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 9.09%
  4. Pain: 1 person, 9.09%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%
  6. Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 9.09%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%
  8. Heavy Or Prolong Menstrual Bleeding: 1 person, 9.09%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Arava and Buspirone hcl?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Arava and Buspirone hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arava:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Buspirone hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arava and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Buspirone hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on leflunomide and buspirone hydrochloride (the active ingredients of Arava and Buspirone hcl, respectively), and Arava and Buspirone hcl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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