Arava and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arava (leflunomide) and Compazine (prochlorperazine maleate). Common drug interactions include wheezing among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Arava and Compazine. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in nausea and vomiting. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Aug, 12, 2026

68 people who take Arava and Compazine together, and have interactions are studied.

What are the common drug interactions of Arava and Compazine, by gender? *:

female:

Wheezing (a high-pitched whistling sound made while you breath)
Abdominal pain
Appetite disorder (abnormal eating habits)
Dry skin
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oedema (fluid collection in tissue)
Oral pain
Pain
Rash
Skin disorder (skin disease)

male:

Back pain
Pain in extremity
Back disorder
Back injury
Bone disorder
Calculus ureteric (stone in ureter)
Cardiomegaly (increased size of heart than normal)
Cellulitis (infection under the skin)
Compression fracture (fracture due to pressure caused by injury)
Confusional state

What are the common drug interactions of Arava and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypoxia (low oxygen in tissues)
Injection site haematoma (localized swelling filled with blood at injection site)
Respiratory distress (difficulty in breathing)
Weight increased

40-49:

Drug hypersensitivity

50-59:

Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Dizziness
Drug hypersensitivity
Dry skin
Dysphagia (a condition in which swallowing is difficult or painful)
Dysphoria (generalized dissatisfaction with life)
Dyspnoea (difficult or laboured respiration)
Ear pain

60+:

Drug hypersensitivity
Arthralgia (joint pain)
Anaphylactic reaction (serious allergic reaction)
Chills (felling of cold)
Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)

What are the existing conditions these people have? *

Dizziness: 39 people, 57.35%
Pain: 15 people, 22.06%
Weight Decreased: 6 people, 8.82%
Pain In Jaw: 6 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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