Arava and Levemir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arava (leflunomide) and Levemir (insulin detemir recombinant). Common drug interactions include abdominal pain among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Arava and Levemir. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Arava?

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. eHealthMe is studying from 76,040 Arava users. Check the latest studies of Arava.

What is Levemir?

Levemir has active ingredients of insulin detemir recombinant. It is often used in diabetes. eHealthMe is studying from 13,850 Levemir users. Check the latest studies of Levemir.

On Jul, 10, 2026

24 people who take Arava and Levemir together, and have interactions are studied.

What are the common drug interactions of Arava and Levemir, by gender? *:

female:

Abdominal pain
Abdominal mass (localized enlargement or swelling in the human abdomen)
Carbohydrate antigen 125 increased
Dizziness
Haemoglobin decreased
Urinary tract infection
Abdominal wall abscess (abdominal wall infection)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Cholecystitis (infection of gallbladder)

male:

Arthralgia (joint pain)
Oedema peripheral (superficial swelling)
Carbohydrate metabolism disorder (inability of carbohydrate metabolism)
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Decreased interest
Depressed mood
Diabetes mellitus inadequate control
Dysarthria (speech disorder)
Dyspepsia (indigestion)

What are the common drug interactions of Arava and Levemir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anger
Anxiety
Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
Arthralgia (joint pain)
Arthropathy
Asthenia (weakness)
Body temperature increased
Carbohydrate metabolism disorder (inability of carbohydrate metabolism)

50-59:

Arthralgia (joint pain)
Oedema peripheral (superficial swelling)
Abdominal pain
Abdominal wall abscess (abdominal wall infection)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Groin abscess (pus in groin)
Peripheral swelling
Subcutaneous abscess
Urinary tract infection

60+:

Arthralgia (joint pain)
Chondropathy (disease of the cartilage)
Delirium (wild excitement)
Diarrhoea
General physical condition
Hepatitis a
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Hypoglycaemic unconsciousness (unconsciousness due to low blood sugar)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Infection

What are the existing conditions these people have? *

Pain: 6 people, 25.00%
High Blood Pressure: 5 people, 20.83%
High Blood Cholesterol: 4 people, 16.67%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 16.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
Type 1 Diabetes: 2 people, 8.33%
Asthma: 2 people, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.33%
Dizziness: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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