Arg and Levothyroxine sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arg (l - arginine) and Levothyroxine sodium (levothyroxine sodium). Common drug interactions include bladder disorder among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Arg and Levothyroxine sodium. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Arg?

Arg has active ingredients of l - arginine. eHealthMe is studying from 2,666 Arg users. Check the latest studies of Arg.

What is Levothyroxine sodium?

Levothyroxine sodium has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 129,814 Levothyroxine sodium users. Check the latest studies of Levothyroxine sodium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

63 people who take Arg and Levothyroxine sodium together, and have interactions are studied.

Arg and Levothyroxine sodium drug interactions.

What are the common drug interactions of Arg and Levothyroxine Sodium, by gender? *:

female:

Bladder disorder
Blood osmolarity decreased
Cardiac failure
Cerebral haemangioma (blood vessel malformation)
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysgeusia (disorder of the sense of taste)
Fall
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)

male:

Fatigue (feeling of tiredness)
Pyrexia (fever)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pulmonary embolism (blockage of the main artery of the lung)
Urinary tract infection
Abdominal pain
Blood creatinine increased
Breast neoplasm (non cancerous tumour of breast)
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Arg and Levothyroxine Sodium, by age (0-1 to 60+)? *:

0-1:

Device related infection
Gastroenteritis (inflammation of stomach and intestine)
Pyrexia (fever)

2-9:

Cerebral haemangioma (blood vessel malformation)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

10-19:

Blood osmolarity decreased
Headache (pain in head)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Abdominal pain upper
Arthralgia (joint pain)
Cardiac failure congestive
Cough
Diarrhoea
Drug hypersensitivity
Drug ineffective
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)

50-59:

Neutropenia (an abnormally low number of neutrophils)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Poisoning
Respiratory disorder (respiratory disease)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sensory disturbance (sense disturbance)
Sopor (sleep)
Urinary tract infection
Abdominal pain
Drug abuse

60+:

Pruritus (severe itching of the skin)
Aortic valve incompetence
Overdose
Rash papular (redness with papule)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Leukopenia (less number of white blood cells in blood)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Pneumonia

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 12.70%
Pain: 6 people, 9.52%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 7.94%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 6.35%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 4 people, 6.35%
Diabetes: 4 people, 6.35%
Chest Pain: 4 people, 6.35%
Cardiac Disorder: 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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