Arg and Norco drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arg (l - arginine) and Norco (acetaminophen; hydrocodone bitartrate). Common drug interactions include hypersensitivity among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Arg and Norco. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Arg?

Arg has active ingredients of l - arginine. eHealthMe is studying from 2,664 Arg users. Check the latest studies of Arg.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.



On Jul, 16, 2026

24 people who take Arg and Norco together, and have interactions are studied.

Arg and Norco drug interactions.

What are the common drug interactions of Arg and Norco, by gender? *:

female:

  1. Hypersensitivity
  2. Surgery
  3. Asthma
  4. Cerebral disorder (brain disease)
  5. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  6. Headache (pain in head)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nasal septum deviation (deviated nasal septum)
  9. Pelvic adhesions
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

male:

  1. Diarrhoea
  2. Chronic kidney disease
  3. Nervousness
  4. Respiratory disorder (respiratory disease)
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Vertigo
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Alopecia (absence of hair from areas of the body)
  9. Gait disturbance
  10. Abasia (inability to walk)

What are the common drug interactions of Arg and Norco, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Asthma
  2. Cerebral disorder (brain disease)
  3. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  4. Headache (pain in head)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Nasal septum deviation (deviated nasal septum)
  7. Pelvic adhesions
  8. Surgery
  9. Adenomyosis (presence of ectopic glandular tissue found in muscle)
  10. Blood pressure increased

40-49:

  1. Discomfort
  2. Restless legs syndrome (a powerful urge to move your legs)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Yawning (simultaneous inhalation of air and stretching of the eardrums, followed by exhalation of breath)

50-59:

  1. Abasia (inability to walk)
  2. Blood pressure increased
  3. Chest discomfort
  4. Chest pain
  5. Drug abuser
  6. Hospitalisation
  7. Localised infection (infection at the single location)
  8. Osteomyelitis (infection of bone)
  9. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  10. Throat tightness

60+:

  1. Diarrhoea
  2. Chronic kidney disease
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Eating disorder
  6. Drug intolerance (drug sensitivity)
  7. Fatigue (feeling of tiredness)
  8. Hyperglycaemia (high blood sugar)
  9. Hyperlipidaemia (presence of excess lipids in the blood)
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 45.83%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 25.00%
  3. Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 12.50%
  4. Cough: 3 people, 12.50%
  5. Prostate Cancer: 2 people, 8.33%
  6. Neuralgia (pain in one or more nerves): 2 people, 8.33%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 8.33%
  8. Cardiac Disorder: 2 people, 8.33%
  9. Blood Viscosity Increased: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Arg and Norco?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Arg and Norco:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Arg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Norco:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arg and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norco and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on l - arginine and acetaminophen; hydrocodone bitartrate (the active ingredients of Arg and Norco, respectively), and Arg and Norco (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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