Aricept and Byetta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aricept (donepezil hydrochloride) and Byetta (exenatide synthetic). Common drug interactions include hair disorder among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Aricept and Byetta. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Byetta?

Byetta has active ingredients of exenatide synthetic. It is often used in diabetes. eHealthMe is studying from 60,818 Byetta users. Check the latest studies of Byetta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

40 people who take Aricept and Byetta together, and have interactions are studied.

What are the common drug interactions of Aricept and Byetta, by gender? *:

female:

Hair disorder
Heart rate increased
Hemiparesis (weakness on one side of the body)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypoglycaemic unconsciousness (unconsciousness due to low blood sugar)
Hypophagia (reduced food intake)
Insomnia (sleeplessness)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

male:

Weight decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Rash
Renal failure acute (rapid kidney dysfunction)
Anaemia (lack of blood)
Blood glucose fluctuation
Blood glucose increased
Blood triglycerides increased
Bradycardia (abnormally slow heart action)
Chest pain

What are the common drug interactions of Aricept and Byetta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hypertension (high blood pressure)
Blood glucose increased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Weight decreased
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood glucose decreased
Feeling jittery
Gastric cancer (stomach cancer)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

60+:

Blood glucose increased
Weight decreased
Cholecystitis chronic (long lasting infection of gallbladder)
Confusional state
Decreased appetite
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
General physical health deterioration (weak health status)
Injury

What are the existing conditions these people have? *

Type 2 Diabetes: 24 people, 60.00%
High Blood Pressure: 6 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 15.00%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 5 people, 12.50%
Thyroid Diseases: 3 people, 7.50%
Pain: 3 people, 7.50%
Immunodeficiency Common Variable: 3 people, 7.50%
High Blood Cholesterol: 3 people, 7.50%
Depression: 3 people, 7.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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