Aricept and Gabitril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aricept (donepezil hydrochloride) and Gabitril (tiagabine hydrochloride). Common drug interactions include convulsion among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Aricept and Gabitril. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

What is Gabitril?

Gabitril has active ingredients of tiagabine hydrochloride. It is often used in epilepsy. eHealthMe is studying from 2,230 Gabitril users. Check the latest studies of Gabitril.

On Aug, 03, 2026

12 people who take Aricept and Gabitril together, and have interactions are studied.

What are the common drug interactions of Aricept and Gabitril, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Activities of daily living impaired
Blood pressure systolic increased
Collapse of lung (functional breakdown of lung)
Euphoric mood (excessively happy but may become angry or irritable)
Fall
Flight of ideas
Gait disturbance
Hallucination, auditory (perceiving sounds without auditory stimulus)
Headache (pain in head)

male:

Back pain
Bipolar disorder (mood disorder)
Weight increased
Abnormal dreams
Blood sodium decreased
Depression
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nightmare (unpleasant dream)

What are the common drug interactions of Aricept and Gabitril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Blood sodium decreased
Depression
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

60+:

Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Headache (pain in head)
Ill-defined disorder
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Multiple fractures
Psychomotor hyperactivity (feelings of extreme restlessness)
Renal injury (kidney injury)

What are the existing conditions these people have? *

Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 3 people, 25.00%
Sedation: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Dementia (madness): 2 people, 16.67%
Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 8.33%
Sleep Disorder: 1 person, 8.33%
Pain: 1 person, 8.33%
Neuropathy Peripheral (surface nerve damage): 1 person, 8.33%
Neuralgia (pain in one or more nerves): 1 person, 8.33%
Multiple Allergies (allergy to multiple agents): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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