Mefloquine and Paranoia - a phase IV clinical study of FDA data

Summary:

Paranoia is reported as a side effect among people who take Mefloquine (mefloquine hydrochloride), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Nasacort, and have Multiple allergies.

The phase IV clinical study analyzes which people have Paranoia when taking Mefloquine. It is created by eHealthMe based on reports of 899 people who have side effects when taking Mefloquine from the FDA, and is updated regularly.

What is Mefloquine?

Mefloquine has active ingredients of mefloquine hydrochloride. It is often used in malaria. eHealthMe is studying from 991 Mefloquine users. Check the latest studies of Mefloquine.

What is Paranoia?

Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur) is found to be associated with 1,041 drugs and 1,276 conditions by eHealthMe. Check the latest studies of Paranoia.

On Aug, 03, 2026

899 people reported to have side effects when taking Mefloquine.
Among them, 67 people (7.45%) have Paranoia.

Among these 67 people:

How long have people been on Mefloquine when they have Paranoia? *

What is the gender of people who have Paranoia when taking Mefloquine? *

female: 50.77 %
male: 49.23 %

What is the age of people who have Paranoia when taking Mefloquine? *

What are other drugs people take besides Mefloquine? *

What are other side effects people have besides Paranoia? *

Stress And Anxiety: 37 people, 55.22%
Depression: 24 people, 35.82%
Insomnia (sleeplessness): 23 people, 34.33%
Memory Loss: 18 people, 26.87%
Nightmares (unpleasant dreams): 18 people, 26.87%
Dizziness: 16 people, 23.88%
Hallucinations (sensations that appear real but are created by your mind): 16 people, 23.88%
Agitation (state of anxiety or nervous excitement): 14 people, 20.90%
Tinnitus (a ringing in the ears): 13 people, 19.40%
Suicidal Ideation: 13 people, 19.40%

What are the existing conditions these people have? *

Multiple Allergies (allergy to multiple agents): 4 people, 5.97%
Hypersensitivity: 3 people, 4.48%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 4.48%
Occupational Problem Environmental: 1 person, 1.49%

* Approximation only. Some reports may have incomplete information.

Do you take Mefloquine and have Paranoia?

- Check whether Paranoia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Mefloquine:

Mefloquine (991 reports)

Paranoia treatments and more:

Paranoia (23,921 reports)

Browse all side effects of Mefloquine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paranoia:

Paranoia (1,041 drugs)

Browse all the conditions that are associated with Paranoia:

Paranoia (1,276 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mefloquine hydrochloride (the active ingredients of Mefloquine) and Mefloquine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.