Arimidex and Depakote drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arimidex (anastrozole) and Depakote (divalproex sodium). Common drug interactions include nausea among females and amnesia among males.

The phase IV clinical study analyzes what interactions people have when they take Arimidex and Depakote. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 55,581 Depakote users. Check the latest studies of Depakote.

On Jul, 05, 2026

35 people who take Arimidex and Depakote together, and have interactions are studied.

Arimidex and Depakote drug interactions.

What are the common drug interactions of Arimidex and Depakote, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Influenza like illness
Overdose
Pain
Weight increased
Abscess (pus)

male:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Gait disturbance
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Malaise (a feeling of general discomfort or uneasiness)
Pain
Pain in extremity

What are the common drug interactions of Arimidex and Depakote, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Blood pressure fluctuation
Hypertension (high blood pressure)

10-19:

n/a

20-29:

n/a

30-39:

Overdose
Pain
Pain in extremity
Abscess (pus)
Anxiety
Bone disorder
Deformity (disfigurement)
Discomfort
Eating disorder symptom
Emotional distress

40-49:

Gastrointestinal necrosis (destruction of gastrointestinal organ)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Metastases to brain (cancer spreads to brain)
Migraine (headache)
Sepsis (a severe blood infection that can lead to organ failure and death)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Contusion (a type of hematoma of tissue in which capillaries)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fall
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

50-59:

Cellulitis (infection under the skin)
Chest pain
Generalised oedema (swelling all over the body)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Overdose
Pain
Suicide attempt
Tooth loss

60+:

Chest pain
Depression
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Fall
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Weight increased
Feeling hot
Skin burning sensation
Actinomycosis (infection that causes sores, or abscesses)

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 8.57%
Breast Cancer Metastatic: 3 people, 8.57%
Pain: 2 people, 5.71%
Atrophy (wasting away of a part of the body): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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