Arimidex and Methotrexate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arimidex (anastrozole) and Methotrexate sodium (methotrexate sodium). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Arimidex and Methotrexate sodium. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.

What is Methotrexate sodium?

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,679 Methotrexate sodium users. Check the latest studies of Methotrexate sodium.

On Jul, 25, 2026

14 people who take Arimidex and Methotrexate sodium together, and have interactions are studied.

Arimidex and Methotrexate sodium drug interactions.

What are the common drug interactions of Arimidex and Methotrexate Sodium, by gender? *:

female:

Arthralgia (joint pain)
Anaemia (lack of blood)
Muscle disorder (muscle disease)
Osteonecrosis (death of bone)
Osteoporosis (bones weak and more likely to break)
Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthropathy
Asthenia (weakness)

male:

n/a

What are the common drug interactions of Arimidex and Methotrexate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Arthralgia (joint pain)
Bone disorder
Bursa disorder
Gait disturbance
Haemangioma (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in the skin or internal organs)
Hip arthroplasty
Joint stiffness
Muscle disorder (muscle disease)
Osteonecrosis (death of bone)
Cutis laxa (connective tissue disorder in which the skin lacks elasticity and hangs in loose folds)

60+:

Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cerebral atrophy (decrement in size of brain)
Cervical cord compression (compression of spinal cord at site of cervical vertebrae)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dental caries
Disability
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)

What are the existing conditions these people have? *

Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 7.14%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.14%
Allergic Rhinitis: 1 person, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.14%
Breast Cancer Female: 1 person, 7.14%
Breast Cancer Metastatic: 1 person, 7.14%
Breast Cancer Recurrent: 1 person, 7.14%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 7.14%
Discomfort: 1 person, 7.14%
Dry Eyes (lack of adequate tears): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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