Aripiprazole and Nexium 24hr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Aripiprazole (aripiprazole) and Nexium 24hr (esomeprazole magnesium). Common drug interactions include renal injury among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Aripiprazole and Nexium 24hr. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.
What is Aripiprazole?
Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.
What is Nexium 24hr?
Nexium 24hr has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 44,614 Nexium 24hr users. Check the latest studies of Nexium 24hr.
85 people who take Aripiprazole and Nexium 24hr together, and have interactions are studied.

What are the common drug interactions of Aripiprazole and Nexium 24Hr, by gender? *:
female:
- Renal injury (kidney injury)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Dyspepsia (indigestion)
- Renal tubular necrosis (death of kidney tubules)
- Anxiety
- Attention deficit/hyperactivity disorder
- Back pain
- Hysterectomy
- Post-traumatic stress disorder
- Schizoaffective disorder (a mental disorder characterized by disordered thought)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal injury (kidney injury)
- Renal tubular necrosis (death of kidney tubules)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Nephropathy (damage to or disease of a kidney)
- Death
What are the common drug interactions of Aripiprazole and Nexium 24Hr, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
30-39:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Anxiety
- Attention deficit/hyperactivity disorder
- Back pain
- Hysterectomy
- Post-traumatic stress disorder
- Renal tubular necrosis (death of kidney tubules)
- Schizoaffective disorder (a mental disorder characterized by disordered thought)
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Renal injury (kidney injury)
- Dyspepsia (indigestion)
- Renal tubular necrosis (death of kidney tubules)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pharyngitis (inflammation of the pharynx, causing a sore throat)
- Death
50-59:
- Chronic kidney disease
- Renal injury (kidney injury)
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Renal ischaemia (lack of blood supply to kidney)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Essential hypertension (primary hypertension)
- Nephropathy (damage to or disease of a kidney)
- Renal tubular necrosis (death of kidney tubules)
- Coma (state of unconsciousness lasting more than six hours)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
What are the existing conditions these people have? *
- Pain: 32 people, 37.65%
- High Blood Pressure: 26 people, 30.59%
- High Blood Cholesterol: 24 people, 28.24%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 14 people, 16.47%
- Inflammation: 13 people, 15.29%
- Bipolar Disorder (mood disorder): 12 people, 14.12%
- Cardiac Disorder: 11 people, 12.94%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 10 people, 11.76%
- Infection: 10 people, 11.76%
- Sleep Disorder: 9 people, 10.59%
* Approximation only. Some reports may have incomplete information.
Do you take Aripiprazole and Nexium 24hr?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Aripiprazole (39,143 reports)
- Nexium 24hr (44,614 reports)
Browse all drug interactions of Aripiprazole and Nexium 24hr:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Aripiprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nexium 24hr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aripiprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium 24hr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
- Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on aripiprazole and esomeprazole magnesium (the active ingredients of Aripiprazole and Nexium 24hr, respectively), and Aripiprazole and Nexium 24hr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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