Asa and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asa (aspirin) and Rocephin (ceftriaxone sodium). Common drug interactions include joint swelling among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Asa and Rocephin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Asa?

Asa has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 32,557 Asa users. Check the latest studies of Asa.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 15, 2026

16 people who take Asa and Rocephin together, and have interactions are studied.

What are the common drug interactions of Asa and Rocephin, by gender? *:

female:

Joint swelling
Kidney fibrosis (excess fibrous connective tissue in kidney)
Leukopenia (less number of white blood cells in blood)
Loose tooth
Loss of consciousness
Lung adenocarcinoma (a form of non-small cell lung cancer)
Lymphadenopathy (disease or enlargement of lymph nodes)
Malignant neoplasm progression (cancer tumour came back)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mucosal inflammation (infection of mucous membrane)

male:

Fatigue (feeling of tiredness)
Pulmonary embolism (blockage of the main artery of the lung)
Mitral valve stenosis (narrowing of mitral valve)
Pyrexia (fever)
Abdominal pain
Aortic arteriosclerosis (hardening of the aortic arteries)
Arthralgia (joint pain)
Blood albumin decreased
Cardiac failure
Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Asa and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Endocarditis (inflammation in heart muscle)
Fatigue (feeling of tiredness)
Laryngomalacia (a congenital softening of the tissues of the larynx)
Pericardial effusion (fluid around the heart)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory distress (difficulty in breathing)
Respiratory tract oedema (swelling of respiratory tract due to excess fluid collection in tissue)
Streptococcal bacteraemia (a bacterial infection of blood)
Extubation

20-29:

n/a

30-39:

n/a

40-49:

Loss of consciousness
Lymphadenopathy (disease or enlargement of lymph nodes)
Malignant neoplasm progression (cancer tumour came back)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Mucosal inflammation (infection of mucous membrane)
Muscle spasms (muscle contraction)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasal odour
Nephrolithiasis (calculi in the kidneys)

50-59:

Abdominal pain
Acute myocardial infarction (acute heart attack)
Arthralgia (joint pain)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cellulitis (infection under the skin)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Lung adenocarcinoma (a form of non-small cell lung cancer)
Oedema (fluid collection in tissue)

60+:

Haemophilus bacteraemia (bacterial infection by haemophilus influenzae)
Hepatocellular injury (liver injury)
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Concomitant disease progression (progress in accompanying disease)
Diarrhoea
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram qt prolonged
Feeling cold

What are the existing conditions these people have? *

Cough: 3 people, 18.75%
Hypersensitivity: 3 people, 18.75%
Multiple Myeloma (cancer of the plasma cells): 3 people, 18.75%
Depression: 3 people, 18.75%
Nausea (feeling of having an urge to vomit): 2 people, 12.50%
High Blood Pressure: 2 people, 12.50%
Blood Glucose Decreased: 2 people, 12.50%
Cardiac Failure Chronic: 2 people, 12.50%
Insulin-Requiring Type 2 Diabetes Mellitus: 2 people, 12.50%
Pain: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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