Astelin and Estrace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Astelin (azelastine hydrochloride) and Estrace (estradiol). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Astelin and Estrace. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.

On Jul, 20, 2026

77 people who take Astelin and Estrace together, and have interactions are studied.

What are the common drug interactions of Astelin and Estrace, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Back pain
Hypotension (abnormally low blood pressure)
Myalgia (muscle pain)
Visual impairment
Asthma
Headache (pain in head)
Nasopharyngitis (inflammation of the nasopharynx)
Dizziness
Fall

male:

n/a

What are the common drug interactions of Astelin and Estrace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Heart rate increased

40-49:

Arteriovenous fistula site haemorrhage
Cardiomegaly (increased size of heart than normal)
Deep vein thrombosis postoperative (blood clot in a major vein that usually develops in the legs and/or pelvis after operation)
Fluid overload (too much fluid in the blood)
Groin pain
Heart rate increased
Hypotension (abnormally low blood pressure)
Influenza
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Multi-organ disorder (multiple organ disease)

50-59:

Asthenia (weakness)
Dizziness
Dyspnoea (difficult or laboured respiration)
Fall
Vertigo
Arthralgia (joint pain)
Myalgia (muscle pain)
Abdominal distension
Constipation
Pain

60+:

Anxiety
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hypotension (abnormally low blood pressure)
Iron deficiency anaemia
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Decreased appetite

What are the existing conditions these people have? *

Hypersensitivity: 12 people, 15.58%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 11.69%
Pain: 9 people, 11.69%
Stress And Anxiety: 7 people, 9.09%
Nausea (feeling of having an urge to vomit): 7 people, 9.09%
Back Pain: 7 people, 9.09%
Immunodeficiency Common Variable: 7 people, 9.09%
Sleep Disorder: 7 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 7 people, 9.09%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 7 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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