Astelin and Nuvigil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Astelin (azelastine hydrochloride) and Nuvigil (armodafinil). Common drug interactions include gastritis among females and therapeutic response unexpected among males.

The phase IV clinical study analyzes what interactions people have when they take Astelin and Nuvigil. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

What is Nuvigil?

Nuvigil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 23,669 Nuvigil users. Check the latest studies of Nuvigil.

On Jul, 11, 2026

91 people who take Astelin and Nuvigil together, and have interactions are studied.

What are the common drug interactions of Astelin and Nuvigil, by gender? *:

female:

Gastritis (inflammation of stomach)
Gout (uric acid crystals building up in the body)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypokalaemia (low potassium)
Meibomian gland dysfunction (dry eyes)
Migraine (headache)
Neuritis (inflammation of nerve)
Osteopenia (a condition where bone mineral density is lower than normal)
Pyrexia (fever)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)

male:

Therapeutic response unexpected
Nasopharyngitis (inflammation of the nasopharynx)
Overdose
Postoperative wound infection
Soliloquy
Suicidal ideation
Vitamin d deficiency
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)

What are the common drug interactions of Astelin and Nuvigil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Tinnitus (a ringing in the ears)

30-39:

Ovarian cyst (fluid filled sac of the ovary)
Pruritus (severe itching of the skin)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Skin discolouration (change of skin colour)
Thyroid mass
Trigger finger
Anxiety
Coma (state of unconsciousness lasting more than six hours)
Hysterectomy

40-49:

Headache (pain in head)
Back pain
Flushing (the warm, red condition of human skin)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Abnormal dreams
Soliloquy
Suicidal ideation
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

Rash
Ankle fracture
Anxiety
Asthenia (weakness)
Blood pressure increased
Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Disturbance in attention

60+:

Terminal insomnia (a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired)
Catecholamines urine increased
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Constipation
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Oropharyngeal pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 30 people, 32.97%
Drowsiness: 9 people, 9.89%
Hypersensitivity: 8 people, 8.79%
Depression: 6 people, 6.59%
Sleep Apnea Syndrome: 5 people, 5.49%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.49%
Asthma: 5 people, 5.49%

* Approximation only. Some reports may have incomplete information.

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