Astelin and Probiotic drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Astelin (azelastine hydrochloride) and Probiotic (bacillus coagulans). Common drug interactions include hemiplegic migraine among females and pneumothorax among males.
The phase IV clinical study analyzes what interactions people have when they take Astelin and Probiotic. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.
What is Astelin?
Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.
What is Probiotic?
Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,461 Probiotic users. Check the latest studies of Probiotic.
80 people who take Astelin and Probiotic together, and have interactions are studied.

What are the common drug interactions of Astelin and Probiotic, by gender? *:
female:
- Hemiplegic migraine (migraine attacks occurring in two or more people in the same family who experience weakness on one side of body)
- Hyperhidrosis (abnormally increased sweating)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Knee arthroplasty
- Lymphocytic hypophysitis (inflammation of the pituitary gland)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Muscular weakness (muscle weakness)
- Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
- Nasal dryness (dry nose)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
male:
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Anaemia (lack of blood)
- Agitation (state of anxiety or nervous excitement)
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood albumin decreased
- Blood sodium decreased
- Body height decreased
What are the common drug interactions of Astelin and Probiotic, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Neuropathy peripheral (surface nerve damage)
30-39:
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Rash
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Anxiety
- Arthralgia (joint pain)
- Back pain
- Blood sodium increased
- Bone pain
40-49:
- Sinusitis (inflammation of sinus)
50-59:
- Uveitis (inflammation of the uvea)
- Abscess (pus)
- Asthma
- Blood copper increased
- Cellulitis (infection under the skin)
- Cough
- Fall
- Hypoaesthesia (reduced sense of touch or sensation)
- Leukocytosis (increased white blood cells)
- Migraine (headache)
60+:
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Anaemia (lack of blood)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Acute respiratory failure
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Ageusia (loss of taste functions of the tongue)
- Arthralgia (joint pain)
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Asthma
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 31 people, 38.75%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 25.00%
- Immunodeficiency Common Variable: 6 people, 7.50%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 6.25%
- Sleep Disorder: 4 people, 5.00%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 5.00%
- Hypersensitivity: 4 people, 5.00%
- Drowsiness: 4 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Astelin and Probiotic?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Astelin and Probiotic:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Astelin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Probiotic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Astelin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Probiotic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on azelastine hydrochloride and bacillus coagulans (the active ingredients of Astelin and Probiotic, respectively), and Astelin and Probiotic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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