Astepro and Pataday drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Astepro (azelastine hydrochloride) and Pataday (olopatadine hydrochloride). Common drug interactions include constipation among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Astepro and Pataday. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Astepro?

Astepro has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 3,336 Astepro users. Check the latest studies of Astepro.

What is Pataday?

Pataday has active ingredients of olopatadine hydrochloride. It is often used in allergies. eHealthMe is studying from 8,288 Pataday users. Check the latest studies of Pataday.

On Jul, 10, 2026

35 people who take Astepro and Pataday together, and have interactions are studied.

What are the common drug interactions of Astepro and Pataday, by gender? *:

female:

Constipation
Fatigue (feeling of tiredness)
Headache (pain in head)
Arthralgia (joint pain)
Dizziness
Myalgia (muscle pain)
Pruritus (severe itching of the skin)
Adenoma benign (non-cancerous tumour -secreting)
Blood pressure increased
Dry skin

male:

Diarrhoea
Asthenia (weakness)
Migraine (headache)
Urinary tract infection
Chills (felling of cold)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Blood pressure systolic increased
Bradycardia (abnormally slow heart action)

What are the common drug interactions of Astepro and Pataday, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Optic neuritis (optic nerve inflammation)
Pruritus (severe itching of the skin)
Arthralgia (joint pain)
Chest discomfort
Chest pain
Dry mouth
Dry skin
Dyspnoea (difficult or laboured respiration)
Ear discomfort

40-49:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Fatigue (feeling of tiredness)
Influenza like illness
Injection site reaction
Myalgia (muscle pain)

50-59:

Skin irritation
Squamous cell carcinoma (a cancer of a kind of epithelial cell)
Staphylococcal infection (an infection with staphylococcus bacteria)
Streptococcal infection
Syncope (loss of consciousness with an inability to maintain postural tone)
Thyroid cancer
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Arthralgia (joint pain)
Asthma
Corneal disorder

60+:

Diarrhoea
Dizziness
Transaminases increased
Uveitis (inflammation of the uvea)
Acquired oesophageal web (structural abnormalities in the oesophagus)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Blood pressure systolic increased
Bradycardia (abnormally slow heart action)
Cough
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Asthma: 12 people, 34.29%
Stress And Anxiety: 5 people, 14.29%
High Blood Pressure: 5 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 14.29%
Seasonal Allergy (allergic condition due to certain season): 4 people, 11.43%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 11.43%
Migraine (headache): 4 people, 11.43%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 11.43%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 8.57%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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