Cisplatin and Hypotonia - a phase IV clinical study of FDA data
Summary:
Hypotonia is reported as a side effect among people who take Cisplatin (cisplatin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Cyclophosphamide, and have Non-hodgkin's lymphoma.
The phase IV clinical study analyzes which people have Hypotonia when taking Cisplatin. It is created by eHealthMe based on reports of 92,672 people who have side effects when taking Cisplatin from the FDA, and is updated regularly.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
What is Hypotonia?
Hypotonia (low muscle tone) is found to be associated with 835 drugs and 1,765 conditions by eHealthMe. Check the latest studies of Hypotonia.
92,672 people reported to have side effects when taking Cisplatin.
Among them, 52 people (0.06%) have Hypotonia.

Among these 52 people:
How long have people been on Cisplatin when they have Hypotonia? *
- < 1 month: 28.57 %
- 1 - 6 months: 71.43 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Hypotonia when taking Cisplatin? *
- female: 16.33 %
- male: 83.67 %
What is the age of people who have Hypotonia when taking Cisplatin? *
- 0-1: 4.76 %
- 2-9: 4.76 %
- 10-19: 2.38 %
- 20-29: 0.0 %
- 30-39: 2.38 %
- 40-49: 7.14 %
- 50-59: 14.29 %
- 60+: 64.29 %
What are other drugs people take besides Cisplatin? *
- Cyclophosphamide: 17 people, 32.69%
- Dexamethasone: 15 people, 28.85%
- Cytarabine: 15 people, 28.85%
- Prednisone: 14 people, 26.92%
- Allopurinol: 13 people, 25.00%
- Bendamustine Hydrochloride: 8 people, 15.38%
- Bendamustine: 7 people, 13.46%
- Doxorubicin Hydrochloride: 6 people, 11.54%
- Etoposide: 6 people, 11.54%
- Vincristine Sulfate: 5 people, 9.62%
What are other side effects people have besides Hypotonia? *
- Fever: 17 people, 32.69%
- Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 15 people, 28.85%
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 14 people, 26.92%
- Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 14 people, 26.92%
- Fatigue (feeling of tiredness): 12 people, 23.08%
- General Physical Health Deterioration (weak health status): 9 people, 17.31%
- Dizziness: 9 people, 17.31%
- Pulmonary Embolism (blockage of the main artery of the lung): 6 people, 11.54%
- Weakness: 5 people, 9.62%
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 4 people, 7.69%
What are the existing conditions these people have? *
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 14 people, 26.92%
- Lung Cancer - Non-Small Cell (lung cancer): 5 people, 9.62%
- Gastric Cancer (stomach cancer): 3 people, 5.77%
- Brain Neoplasm (tumour of brain): 2 people, 3.85%
- Brain Neoplasm Malignant (brain cancer tumour): 2 people, 3.85%
- Nausea And Vomiting: 2 people, 3.85%
- Nausea (feeling of having an urge to vomit): 2 people, 3.85%
- Diabetes: 2 people, 3.85%
- High Blood Pressure: 2 people, 3.85%
- Tonsil Cancer: 1 person, 1.92%
* Approximation only. Some reports may have incomplete information.
Do you take Cisplatin and have Hypotonia?
- Check whether Hypotonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Cisplatin:
- Cisplatin (92,837 reports)
Hypotonia treatments and more:
- Hypotonia (14,614 reports)
How severe was Hypotonia and when was it recovered:
Expand to all the drugs that have ingredients of cisplatin:
- Hypotonia and drugs with ingredients of cisplatin (32 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hypotonia:
- Hypotonia (835 drugs)
Browse all the conditions that are associated with Hypotonia:
- Hypotonia (1,765 conditions)
Related publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisplatin (the active ingredients of Cisplatin) and Cisplatin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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