Atarax and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atarax (hydroxyzine hydrochloride) and Actigall (ursodiol). Common drug interactions include dyspnoea exertional among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Atarax and Actigall. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 04, 2026

49 people who take Atarax and Actigall together, and have interactions are studied.

What are the common drug interactions of Atarax and Actigall, by gender? *:

female:

Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Haemodynamic instability (disturbances in the blood movement in our body)
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
Pleural effusion (water on the lungs)
Sputum discoloured
Abdominal pain upper
Acute myocardial infarction (acute heart attack)
Chest pain
Dysphagia (a condition in which swallowing is difficult or painful)

male:

Diarrhoea
Blood urea increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Acidosis (build-up of carbon dioxide in the blood)
Acute respiratory distress syndrome
Anaemia (lack of blood)
Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
Blood creatinine increased
Bronchial haemorrhage (bleeding in bronchia)

What are the common drug interactions of Atarax and Actigall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Pregnancy
Premature labour
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

n/a

30-39:

Blood urea increased
Pneumonia
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Pyrexia (fever)
Acidosis (build-up of carbon dioxide in the blood)
Acute respiratory distress syndrome
Anaemia (lack of blood)
Asthenia (weakness)
Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
Blood creatinine increased

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Skin fibrosis (fibrous tissue formation on skin)

50-59:

Nasopharyngitis (inflammation of the nasopharynx)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Night sweats (sweating in night)
Pancreatitis (inflammation of pancreas)
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Productive cough
Pulmonary toxicity (side effects on the lungs)
Red blood cell count decreased
Renal impairment (severely reduced kidney function)

60+:

Purpura (purplish discoloration of the skin)
Rash pruritic (redness with itching)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Rash
Type 2 diabetes mellitus
Anaphylactic reaction (serious allergic reaction)
Angioedema (rapid swelling of the dermis)
Areflexia (absence of a reflex)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Breath sounds

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 14 people, 28.57%
Cough: 14 people, 28.57%
Pain: 13 people, 26.53%
High Blood Pressure: 12 people, 24.49%
Cystic Fibrosis (disease of the secretary glands): 12 people, 24.49%
Itching: 11 people, 22.45%
Wheezing (a high-pitched whistling sound made while you breath): 11 people, 22.45%
Nasal Discomfort: 10 people, 20.41%
Inflammation: 9 people, 18.37%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 9 people, 18.37%

* Approximation only. Some reports may have incomplete information.

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