Trileptal and Lamisil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Trileptal (oxcarbazepine) and Lamisil (terbinafine hydrochloride). Common drug interactions include chronic kidney disease among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Trileptal and Lamisil. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Trileptal?
Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. eHealthMe is studying from 23,558 Trileptal users. Check the latest studies of Trileptal.
What is Lamisil?
Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
35 people who take Trileptal and Lamisil together, and have interactions are studied.

What are the common drug interactions of Trileptal and Lamisil, by gender? *:
female:
- Chronic kidney disease
- Renal injury (kidney injury)
- Haematochezia (passage of stools containing blood)
- Renal failure (kidney dysfunction)
- Death
male:
- Headache (pain in head)
- Fall
- Contusion (a type of hematoma of tissue in which capillaries)
- Depression
- Dry mouth
- Hypermetabolism (abnormal increase in the body's basal metabolic rate)
- Injury
- Joint injury
- Migraine (headache)
- Physical assault
What are the common drug interactions of Trileptal and Lamisil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Aspartate aminotransferase increased
- Blood creatine phosphokinase increased
- Muscle spasms (muscle contraction)
- Pain in extremity
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
10-19:
n/a
20-29:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
30-39:
- Bacteriuria (presence of bacteria in urine)
- Bedridden
- Blood alkaline phosphatase decreased
- Blood calcium decreased
- Blood chloride increased
- Blood creatinine decreased
- Blood urea decreased
- Carbon dioxide decreased
- Cystitis (inflammation of the wall of the bladder)
- Gait disturbance
40-49:
- Hypertension (high blood pressure)
50-59:
- Dry mouth
- Fall
- Hypermetabolism (abnormal increase in the body's basal metabolic rate)
- Injury
- Joint injury
- Migraine (headache)
- Physical assault
- Road traffic accident
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Snoring
60+:
- Chronic kidney disease
- Renal injury (kidney injury)
What are the existing conditions these people have? *
- Pain: 26 people, 74.29%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 8.57%
- Nail Tinea (fungal infection of nail): 2 people, 5.71%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Trileptal and Lamisil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Trileptal and Lamisil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Trileptal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lamisil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Trileptal and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lamisil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on oxcarbazepine and terbinafine hydrochloride (the active ingredients of Trileptal and Lamisil, respectively), and Trileptal and Lamisil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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