Ativan and Estrogel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ativan (lorazepam) and Estrogel (estradiol). Common drug interactions include constipation among females and general physical health deterioration among males.

The phase IV clinical study analyzes what interactions people have when they take Ativan and Estrogel. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.

What is Estrogel?

Estrogel has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 2,922 Estrogel users. Check the latest studies of Estrogel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

39 people who take Ativan and Estrogel together, and have interactions are studied.

What are the common drug interactions of Ativan and Estrogel, by gender? *:

female:

Constipation
Drug hypersensitivity
Dysgeusia (disorder of the sense of taste)
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Vomiting
Abdominal distension
Dysphonia (speech disorder attributable to a disorder of phonation)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

General physical health deterioration (weak health status)
Haemoglobin decreased
Nausea (feeling of having an urge to vomit)
Vomiting
Flatulence (flatus expelled through the anus)
Abdominal pain
Blood potassium decreased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Eating disorder

What are the common drug interactions of Ativan and Estrogel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Blood potassium decreased
Constipation
Diarrhoea
Hydronephrosis (water inside the kidney)
Intestinal obstruction
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

50-59:

Eating disorder
Eye pain
Frequent bowel movements
Gait disturbance
Headache (pain in head)
Hydronephrosis (water inside the kidney)
Hypoaesthesia (reduced sense of touch or sensation)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oesophageal dilatation (enlarged oesophagus)
Retinal disorder (disease of retina)

60+:

Hyperhidrosis (abnormally increased sweating)
Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Endocrine neoplasm (tumour of endocrine glands)
Frequent bowel movements
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Oropharyngeal pain
Pericarditis (inflammation of the pericardium)
Cellulitis (infection under the skin)
Pain

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9 people, 23.08%
Joint Pain: 9 people, 23.08%
Osteoporosis (bones weak and more likely to break): 6 people, 15.38%
Pain: 5 people, 12.82%
Urinary Tract Infection: 4 people, 10.26%
Hypersensitivity: 4 people, 10.26%
Depression: 3 people, 7.69%
Sleep Disorder: 3 people, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.69%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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