Mitoxantrone and Lasix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mitoxantrone (mitoxantrone hydrochloride) and Lasix (furosemide). Common drug interactions include pyrexia among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Mitoxantrone and Lasix. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Mitoxantrone?

Mitoxantrone has active ingredients of mitoxantrone hydrochloride. eHealthMe is studying from 8,125 Mitoxantrone users. Check the latest studies of Mitoxantrone.

What is Lasix?

Lasix has active ingredients of furosemide. It is often used in swelling. eHealthMe is studying from 210,439 Lasix users. Check the latest studies of Lasix.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

72 people who take Mitoxantrone and Lasix together, and have interactions are studied.

Mitoxantrone and Lasix drug interactions.

What are the common drug interactions of Mitoxantrone and Lasix, by gender? *:

female:

Pyrexia (fever)
Neutropenia (an abnormally low number of neutrophils)
Dyspnoea (difficult or laboured respiration)
Cardiac arrest
Encephalopathy (functioning of the brain is affected by some agent or condition)
Failure to thrive (inadequate weight gain and physical growth in children)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Loss of consciousness
Pneumonia
Diarrhoea

male:

Pneumonia
Dyspnoea (difficult or laboured respiration)
Pain
Confusional state
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Cardiac failure congestive
Deformity (disfigurement)
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Mitoxantrone and Lasix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pericardial effusion (fluid around the heart)
Thrombocytopenia (decrease of platelets in blood)
Venoocclusive liver disease (small veins in the liver are obstructed)

10-19:

Cardiogenic shock (inadequate circulation of blood)
Blood triglycerides increased
Cardiomyopathy (weakening of the heart muscle)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Diarrhoea
Enterococcal infection
Respiratory distress (difficulty in breathing)
Serum ferritin increased
Subdural haemorrhage (bleeding between the skull and the surface of the brain)
Abdominal pain lower

20-29:

Abdominal distension
Abdominal pain
Abdominal tenderness
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Anaemia (lack of blood)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Atelectasis (partial or complete collapse of the lung)
Blood albumin decreased
Blood albumin increased

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Blood lactate dehydrogenase increased
Bone pain
Death
Disease progression
Hypophagia (reduced food intake)
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)

50-59:

Cerebellar infarction (impaired blood circulation to cerebellum)
Electrocardiogram qt prolonged
Lung infection
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)
Drug eruption (adverse drug reaction of the skin)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Pneumonia

60+:

Pneumonia
Dyspnoea (difficult or laboured respiration)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
Cardiac failure congestive
Cough
Deformity (disfigurement)
Dehydration (dryness resulting from the removal of water)
Dizziness

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 12 people, 16.67%
Prostate Cancer Metastatic: 10 people, 13.89%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 9.72%
High Blood Pressure: 7 people, 9.72%
Bone Disorder: 7 people, 9.72%
Pain: 5 people, 6.94%
Abdominal Discomfort: 5 people, 6.94%
Rashes (redness): 4 people, 5.56%
Nausea (feeling of having an urge to vomit): 4 people, 5.56%
Insomnia (sleeplessness): 4 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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