Atovaquone and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atovaquone (atovaquone) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include hospitalisation among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Atovaquone and Spiriva. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Atovaquone?

Atovaquone has active ingredients of atovaquone. eHealthMe is studying from 5,786 Atovaquone users. Check the latest studies of Atovaquone.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Jul, 26, 2026

54 people who take Atovaquone and Spiriva together, and have interactions are studied.

Atovaquone and Spiriva drug interactions.

What are the common drug interactions of Atovaquone and Spiriva, by gender? *:

female:

Hospitalisation
Pneumonia viral
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Drug ineffective
Dyspepsia (indigestion)
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Injection site erythema (redness at injection site)

male:

Pneumonia
Thrombocytopenia (decrease of platelets in blood)
Acute respiratory failure
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Arthralgia (joint pain)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Brain natriuretic peptide increased
Cardiac failure
Chest discomfort

What are the common drug interactions of Atovaquone and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypertension (high blood pressure)

30-39:

Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)

40-49:

n/a

50-59:

Oedema peripheral (superficial swelling)
Blood bilirubin increased
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cardiac murmur (an heart sound in valve abnormality)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hepatic enzyme increased
Hepatotoxicity (chemical-driven liver damage)
Hypomania (a mild form of mania, marked by elation and hyperactivity)
Jaundice cholestatic

60+:

Haemoglobin decreased
Pneumonia
Pyrexia (fever)
Right ventricular failure (right half of the heart fails to work)
Abdominal pain
Abscess (pus)
Acute respiratory failure
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Arrhythmia (irregular heartbeat)

What are the existing conditions these people have? *

Hiv Infection: 11 people, 20.37%
Psychotic Disorder: 9 people, 16.67%
Hypomania (a mild form of mania, marked by elation and hyperactivity): 9 people, 16.67%
Depression: 9 people, 16.67%
Immunodeficiency Common Variable: 8 people, 14.81%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 8 people, 14.81%
Pain In Extremity: 5 people, 9.26%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 5 people, 9.26%
Multiple Myeloma (cancer of the plasma cells): 4 people, 7.41%
Asthma: 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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