Atripla and Jardiance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Atripla (efavirenz; emtricitabine; tenofovir disoproxil fumarate) and Jardiance (empagliflozin). Common drug interactions include anhedonia among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Atripla and Jardiance. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Atripla?

Atripla has active ingredients of efavirenz; emtricitabine; tenofovir disoproxil fumarate. It is often used in hiv infection. eHealthMe is studying from 36,036 Atripla users. Check the latest studies of Atripla.

What is Jardiance?

Jardiance has active ingredients of empagliflozin. It is often used in hyperglycemia. eHealthMe is studying from 44,457 Jardiance users. Check the latest studies of Jardiance.

On Jul, 15, 2026

26 people who take Atripla and Jardiance together, and have interactions are studied.

Atripla and Jardiance drug interactions.

What are the common drug interactions of Atripla and Jardiance, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Chronic kidney disease
Foot fracture
Pneumonia
Asthenia (weakness)

male:

Emotional distress
Pain
Multiple fractures
Osteonecrosis (death of bone)
Tooth loss
Blood creatinine increased
Nephropathy (damage to or disease of a kidney)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Impaired driving ability

What are the common drug interactions of Atripla and Jardiance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Pain
Bone disorder
Chronic kidney disease
Nephropathy (damage to or disease of a kidney)
Osteopenia (a condition where bone mineral density is lower than normal)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Foot fracture
Pain
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Bone density decreased
Bone loss

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Fatigue (feeling of tiredness)
Renal failure (kidney dysfunction)
Pneumonia
Asthenia (weakness)
Anaemia (lack of blood)

60+:

Chronic kidney disease
Emotional distress
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Impaired driving ability
Nightmare (unpleasant dream)
Nephropathy (damage to or disease of a kidney)
Pain
Bone density decreased

What are the existing conditions these people have? *

Type 2 Diabetes: 5 people, 19.23%
High Blood Pressure: 3 people, 11.54%
Stress And Anxiety: 2 people, 7.69%
Pain: 2 people, 7.69%
Inflammation: 2 people, 7.69%
Hypersensitivity: 2 people, 7.69%
High Blood Cholesterol: 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Depression: 2 people, 7.69%
Bacterial Infection: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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