Symbicort and Diastolic dysfunction - a phase IV clinical study of FDA data

Summary:

Diastolic dysfunction is reported as a side effect among people who take Symbicort (budesonide; formoterol fumarate dihydrate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Spiriva, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Diastolic dysfunction when taking Symbicort. It is created by eHealthMe based on reports of 112,650 people who have side effects when taking Symbicort from the FDA, and is updated regularly.

What is Symbicort?

Symbicort has active ingredients of budesonide; formoterol fumarate dihydrate. It is often used in asthma. eHealthMe is studying from 114,792 Symbicort users. Check the latest studies of Symbicort.

What is Diastolic dysfunction?

Diastolic dysfunction is found to be associated with 680 drugs and 630 conditions by eHealthMe. Check the latest studies of Diastolic dysfunction.

On Jul, 15, 2026

112,650 people reported to have side effects when taking Symbicort.
Among them, 38 people (0.03%) have Diastolic dysfunction.

Could Symbicort cause Diastolic dysfunction?

Among these 38 people:

How long have people been on Symbicort when they have Diastolic dysfunction? *

What is the gender of people who have Diastolic dysfunction when taking Symbicort? *

female: 35.14 %
male: 64.86 %

What is the age of people who have Diastolic dysfunction when taking Symbicort? *

What are other drugs people take besides Symbicort? *

What are other side effects people have besides Diastolic dysfunction? *

Dyspnea (difficult or laboured breathing): 20 people, 52.63%
Cough: 12 people, 31.58%
High Blood Pressure: 12 people, 31.58%
Pain In Extremity: 11 people, 28.95%
Weight Decreased: 11 people, 28.95%
Pneumonia: 11 people, 28.95%
Fatigue (feeling of tiredness): 11 people, 28.95%
Cardiac Failure Congestive: 10 people, 26.32%
Oedema Peripheral (superficial swelling): 10 people, 26.32%
Pleural Effusion (water on the lungs): 9 people, 23.68%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 15.79%
Pain: 5 people, 13.16%
High Blood Pressure: 5 people, 13.16%
Cardiac Failure: 3 people, 7.89%
Dyslipidaemia (abnormal amount of lipids): 2 people, 5.26%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 5.26%
Diabetes: 2 people, 5.26%
Depression: 2 people, 5.26%
Multiple Myeloma (cancer of the plasma cells): 2 people, 5.26%
Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Symbicort and have Diastolic dysfunction?

- Check whether Diastolic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Symbicort:

Symbicort (114,792 reports)

Diastolic dysfunction treatments and more:

Diastolic dysfunction (4,665 reports)

How severe was Diastolic dysfunction and when was it recovered:

Diastolic dysfunction in Symbicort

Expand to all the drugs that have ingredients of budesonide; formoterol fumarate dihydrate:

Diastolic dysfunction and drugs with ingredients of budesonide; formoterol fumarate dihydrate (38 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Symbicort:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diastolic dysfunction:

Diastolic dysfunction (680 drugs)

Browse all the conditions that are associated with Diastolic dysfunction:

Diastolic dysfunction (630 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on budesonide; formoterol fumarate dihydrate (the active ingredients of Symbicort) and Symbicort (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.